Condition (MeSH)
Keratoconjunctivitis Sicca
ClinicalTrials.gov lists 85 trials for Keratoconjunctivitis Sicca or a narrower condition beneath it.
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Trials per phase
85 of the 85 trials are tagged with Keratoconjunctivitis Sicca itself; the rest are tagged with a narrower condition beneath it.
When did Keratoconjunctivitis Sicca trials start? (23)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 9
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 2 |
| 2024 | 3 |
| 2023 | 1 |
| 2022 | 5 |
| 2021 | 4 |
| 2020 | 5 |
| 2019 | 4 |
| 2018 | 5 |
| 2016 | 9 |
| 2015 | 2 |
Showing 10 of 23 earlier years.
No forecast is made for this condition: it averages 2.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Keratoconjunctivitis Sicca trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 3 |
| Phase 1/2 | 2 |
| Phase 2 | 21 |
| Phase 2/3 | 3 |
| Phase 3 | 20 |
| Phase 4 | 11 |
| Not applicable | 20 |
| Observational | 5 |
How many Keratoconjunctivitis Sicca trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Completed | 74 |
| Terminated | 1 |
| Withdrawn | 5 |
| Unknown status | 4 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Keratoconjunctivitis Sicca trials? (12)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Allergan | 4 |
| Oculeve, Inc. | 4 |
| Sun Pharmaceutical Industries Limited | 4 |
| Kala Pharmaceuticals, Inc. | 3 |
| Mimetogen Pharmaceuticals USA, Inc. | 3 |
Showing 5 of 12 sponsors.
Which drugs are being tested for Keratoconjunctivitis Sicca? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Lifitegrast | 3 |
| Loteprednol Etabonate | 3 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Cyclosporine 0.05% | 5 |
| R348 Ophthalmic Solution, 0.2% | 3 |
| Vehicle Ophthalmic Solution | 3 |
| R348 Ophthalmic Solution, 0.5% | 3 |
| 1% Tavilermide Ophthalmic Solution | 2 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Keratoconjunctivitis Sicca trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Cerebrovascular accident | 7 | 6 |
| Osteoarthritis | 5 | 2 |
| Pneumonia | 5 | 5 |
| Breast cancer | 2 | 2 |
| Femur fracture | 2 | 2 |
Showing 5 of 10 adverse events.
Which publications cover Keratoconjunctivitis Sicca? (55)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 55 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.