Condition (MeSH)
Lacrimal Duct Obstruction
ClinicalTrials.gov lists 29 trials for Lacrimal Duct Obstruction or a narrower condition beneath it. Fondation Ophtalmologique Adolphe de Rothschild has the most among industry and government lead sponsors, with 1.
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Trials per phase
29 of the 29 trials are tagged with Lacrimal Duct Obstruction itself; the rest are tagged with a narrower condition beneath it.
When did Lacrimal Duct Obstruction trials start? (15)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1/2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 2 |
| 2023 | 2 |
| 2021 | 2 |
| 2020 | 2 |
| 2019 | 2 |
| 2018 | 5 |
| 2015 | 2 |
| 2009 | 1 |
Showing 10 of 15 earlier years.
No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Lacrimal Duct Obstruction trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 3 | 3 |
| Phase 4 | 3 |
| Not applicable | 13 |
| Observational | 9 |
How many Lacrimal Duct Obstruction trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 2 |
| Completed | 18 |
| Terminated | 1 |
| Unknown status | 5 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Lacrimal Duct Obstruction trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Fondation Ophtalmologique Adolphe de Rothschild | 1 |
Which drugs are being tested for Lacrimal Duct Obstruction? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| DEXMEDETOMIDINE | 1 |
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Proparacaine Hydrochloride ophthalmic solution, USP 0.5% | 2 |
| Balanced Salt Solution | 2 |
| Apo-Latanoprost | 1 |
| Artificial Tears Methylcellulose | 1 |
| Labetolol | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Lacrimal Duct Obstruction? (45)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Topical cyclosporin A 0.05% eye drops for management of symptomatic acquired punctal stenosis: a prospective, controlled clinical study. | Orbit (Amsterdam, Netherlands) | 2024 | Yes |
| A Pilot Nonrandomized Controlled Trial Examining the Use of Artificial Tears on the Radioactivity of Tears After Radioactive Iodine Treatment for Thyroid Cancer. | Thyroid : official journal of the American Thyroid Association | 2024 | Yes |
| A major review of punctal stenosis: Updated anatomy, epidemiology, etiology, and clinical presentation. | Survey of ophthalmology | 2024 | Yes |
| Clinical outcomes and prognostic factors in patients with nasolacrimal duct obstruction or stenosis using dacryoendoscopy. | BMJ open ophthalmology | 2024 | Yes |
| Management of Bi-Punctal Stenosis by One-Snip Punctoplasty Combined with Silicone Intubation. | Orbit (Amsterdam, Netherlands) | 2022 | Yes |
Showing 5 of 45 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.