Condition (MeSH)
Lactose Intolerance
ClinicalTrials.gov lists 51 trials for Lactose Intolerance or a narrower condition beneath it. Ritter Pharmaceuticals, Inc. has the most among industry and government lead sponsors, with 4.
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Trials per phase (log scale)
51 of the 51 trials are tagged with Lactose Intolerance itself; the rest are tagged with a narrower condition beneath it.
When did Lactose Intolerance trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 2 |
| 2024 | 4 |
| 2023 | 1 |
| 2022 | 6 |
| 2021 | 3 |
| 2020 | 1 |
| 2019 | 3 |
| 2018 | 4 |
| 2017 | 2 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 3.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Lactose Intolerance trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
| Phase 2/3 | 1 |
| Phase 3 | 3 |
| Phase 4 | 3 |
| Not applicable | 30 |
| Observational | 12 |
How many Lactose Intolerance trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 3 |
| Completed | 37 |
| Terminated | 1 |
| Withdrawn | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Lactose Intolerance trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Ritter Pharmaceuticals, Inc. | 4 |
| Eurofarma Laboratorios S.A. | 2 |
| a2 Milk Company Ltd. | 2 |
| Children's Hospital and Institute of Child Health, Multan | 1 |
| Danisco | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Lactose Intolerance? (6)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Lactase enzyme | 3 |
| Lactose | 2 |
| Maltodextrin | 1 |
| gaxilose | 1 |
| GED | 1 |
Showing 5 of 6 drugs.
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| RP-G28 | 3 |
| Positive Control | 1 |
| Negative Control | 1 |
| alverine-citrate + simethicone and lactase | 1 |
| Probiotic | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Lactose Intolerance? (146)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Tolerance of protein-hydrolyzed lactose-free A1 milk and A2 milk in lactose-tolerant and lactose-intolerant volunteers: A randomized crossover trial with 2 parallel groups. | Journal of dairy science | 2025 | Yes |
| Exploring exhaled breath biomarkers for lactose intolerance diagnosis: the Lactobreath pilot study protocol. | BMJ open | 2025 | Yes |
| Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase nonpersistent genotype. | The American journal of clinical nutrition | 2024 | Yes |
| Does fecal calprotectin increase may be linked to lactose intolerance in patients with irritable bowel syndrome? | Minerva gastroenterology | 2023 | Yes |
| Gastric Emptying of New-World Milk Containing A1 and A2 Β-Casein Is More Rapid as Compared to Milk Containing Only A2 Β-Casein in Lactose Maldigesters: A Randomized, Cross-Over Trial Using Magnetic Resonance Imaging. | Nutrients | 2023 | Yes |
Showing 5 of 146 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.