Condition (MeSH)
Melena
ClinicalTrials.gov lists 15 trials for Melena or a narrower condition beneath it. Northport Veterans Affairs Medical Center has the most among industry and government lead sponsors, with 1.
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Trials per phase
15 of the 15 trials are tagged with Melena itself; the rest are tagged with a narrower condition beneath it.
When did Melena trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 1 |
| 2024 | 1 |
| 2023 | 1 |
| 2020 | 2 |
| 2019 | 1 |
| 2017 | 1 |
| 2015 | 1 |
| 2014 | 1 |
| 2012 | 2 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Melena trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 2 |
| Phase 4 | 2 |
| Not applicable | 7 |
| Observational | 3 |
How many Melena trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 2 |
| Completed | 8 |
| Terminated | 1 |
| Withdrawn | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Melena trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Northport Veterans Affairs Medical Center | 1 |
Which drugs are being tested for Melena? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| THALIDOMIDE | 1 |
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Terlipressinum | 2 |
| Metclopramide | 2 |
| Early intravenous tranexamic acid administration | 1 |
| Terlipressin & then Dummy | 1 |
| LAR Octreotide | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Melena trials report? (6)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Gastrointestinal Bleeding | 2 | 1 |
| Acute allergic reaction | 1 | 1 |
| Coronavirus | 1 | 1 |
| Hypoxemia | 1 | 1 |
| Melena | 1 | 1 |
Showing 5 of 6 adverse events.
Which publications cover Melena? (21)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Effect of acute upper gastrointestinal bleeding manifestations at admission on the in-hospital outcomes of liver cirrhosis: hematemesis versus melena without hematemesis. | European journal of gastroenterology & hepatology | 2019 | Yes |
| Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation. | Canadian journal of gastroenterology & hepatology | 2018 | Yes |
| Phase III study of pentosanpolysulfate (PPS) in treatment of gastrointestinal tract sequelae of radiotherapy. | American journal of clinical oncology | 2006 | Yes |
| Prognostic factors in upper gastrointestinal bleeding. | Digestive diseases and sciences | 1994 | Yes |
| EFFECTS OF 2'-DEOXY-5-FLUOROURIDINE (NSC-27640) AND 5-FLUOROURACIL (NSC-19893) ON CHILDHOOD LEUKEMIA. | Cancer chemotherapy reports | 1964 | Yes |
Showing 5 of 21 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.