Condition (MeSH)
Menorrhagia
ClinicalTrials.gov lists 200 trials for Menorrhagia or a narrower condition beneath it. Bayer has the most among industry and government lead sponsors, with 18.
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Trials per phase (log scale)
200 of the 200 trials are tagged with Menorrhagia itself; the rest are tagged with a narrower condition beneath it.
When did Menorrhagia trials start? (29)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 14
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 8 |
| 2025 | 11 |
| 2024 | 9 |
| 2023 | 12 |
| 2022 | 4 |
| 2021 | 4 |
| 2020 | 7 |
| 2019 | 6 |
| 2018 | 13 |
| 2017 | 12 |
Showing 10 of 29 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 9 trials starting in 2026 and about 10 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 29 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 129 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Menorrhagia trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 1/2 | 3 |
| Phase 2 | 8 |
| Phase 3 | 44 |
| Phase 4 | 26 |
| Not applicable | 67 |
| Observational | 48 |
How many Menorrhagia trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 9 |
| Recruiting | 17 |
| Active, not recruiting | 2 |
| Completed | 112 |
| Terminated | 21 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Menorrhagia trials? (10)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Bayer | 18 |
| AbbVie | 8 |
| Abbott | 7 |
| Ferring Pharmaceuticals | 5 |
| Gynesonics | 5 |
Showing 5 of 10 sponsors.
Which drugs are being tested for Menorrhagia? (6)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Elagolix | 7 |
| Asoprisnil | 7 |
| Levonorgestrel | 6 |
| Relugolix | 5 |
| Vilaprisan (BAY 1002670) | 4 |
Showing 5 of 6 drugs.
Interventions as named in the registry (9)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| acid tranexamic | 16 |
| Estradiol /norethindrone acetate (E2/NETA) | 9 |
| Ulipristal Acetate - open label | 4 |
| Levonorgestrel IUS | 4 |
| Medroxyprogesterone progesterone acetate (MPA) | 3 |
Showing 5 of 9 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Menorrhagia trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| ANAEMIA | 16 | 5 |
| Menorrhagia | 10 | 5 |
| UTERINE LEIOMYOMA | 10 | 4 |
| Hysterectomy | 8 | 2 |
| Uterine leiomyoma | 8 | 4 |
Showing 5 of 10 adverse events.
Which publications cover Menorrhagia? (197)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Pain Reduction in Linzagolix-Treated Patients With Uterine Fibroids: A Secondary Mediation Analysis of the PRIMROSE 1 and 2 Phase 3 Trials. | BJOG : an international journal of obstetrics and gynaecology | 2025 | Yes |
| Safety and efficacy of vilaprisan in Japanese women with fibroids: The Phase 3 ASTEROID 8 trial. | Women's health (London, England) | 2025 | Yes |
| Relugolix combination therapy in Black/African American women with symptomatic uterine fibroids: LIBERTY Long-Term Extension study. | American journal of obstetrics and gynecology | 2024 | Yes |
| Instruments to Identify Menstrual Complaints and Their Impact on Adolescents: A Systematic Review. | Journal of pediatric and adolescent gynecology | 2024 | Yes |
| A plain language summary of the long-term relugolix combination therapy study for uterine fibroids. | Journal of comparative effectiveness research | 2023 | Yes |
Showing 5 of 197 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.