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Condition (MeSH)

Myopia

ClinicalTrials.gov lists 1,128 trials for Myopia or a narrower condition beneath it. CooperVision, Inc. has the most among industry and government lead sponsors, with 99.

MeSH D009216 Eye Diseases C11
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Phase 1 Phase 1 25 Phase 1/2 Phase 1/2 9 Phase 2 Phase 2 23 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 50 Phase 4 Phase 4 47 Not applicable Not applicable 769 Observational Observational 196 Phase 1 Phase 1 25 Phase 1/2 Phase 1/2 9 Phase 2 Phase 2 23 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 50 Phase 4 Phase 4 47 Not applicable Not applicable 769 Observational Observational 196

Trials per phase (log scale)

1 more section with rows

1,085 of the 1,128 trials are tagged with Myopia itself; the rest are tagged with a narrower condition beneath it.

Get the Myopia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Myopia trials start? (31)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 97

1995: 1 trials (Observational 1) 1996: 1 trials (Phase 3 1) 1997: 1 trials (Phase 3 1) 1999: 1 trials (Observational 1) 2000: 1 trials (Phase 4 1) 2001: 1 trials (Not applicable 1) 2002: 5 trials (Observational 3, Not applicable 1, Phase 1 1) 2003: 7 trials (Not applicable 5, Phase 2 1, Phase 1 1) 2004: 10 trials (Not applicable 8, Phase 4 2) 2005: 18 trials (Observational 6, Not applicable 3, Phase 4 3, Phase 3 2, Phase 2 2, Phase 1 2) 2006: 13 trials (Observational 2, Not applicable 8, Phase 4 1, Phase 2/3 1, Phase 1 1) 2007: 29 trials (Observational 3, Not applicable 17, Phase 4 3, Phase 3 3, Phase 1/2 1, Phase 1 2) 2008: 42 trials (Observational 8, Not applicable 29, Phase 4 3, Phase 3 2) 2009: 35 trials (Observational 2, Not applicable 24, Phase 4 5, Phase 3 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2010: 56 trials (Observational 4, Not applicable 46, Phase 4 1, Phase 3 4, Phase 2 1) 2011: 37 trials (Observational 6, Not applicable 26, Phase 4 2, Phase 3 3) 2012: 37 trials (Observational 1, Not applicable 29, Phase 4 2, Phase 3 1, Phase 1/2 1, Phase 1 3) 2013: 33 trials (Observational 2, Not applicable 29, Phase 4 1, Phase 1 1) 2014: 33 trials (Observational 5, Not applicable 22, Phase 4 4, Phase 3 2) 2015: 37 trials (Observational 4, Not applicable 33) 2016: 43 trials (Observational 7, Not applicable 33, Phase 4 2, Phase 3 1) 2017: 38 trials (Observational 7, Not applicable 27, Phase 4 1, Phase 3 2, Phase 2 1) 2018: 67 trials (Other 1, Observational 15, Not applicable 42, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 2 1, Phase 1/2 1, Phase 1 3) 2019: 53 trials (Other 1, Observational 8, Not applicable 37, Phase 4 2, Phase 3 2, Phase 2 2, Phase 1/2 1) 2020: 54 trials (Observational 18, Not applicable 31, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 1/2 1) 2021: 47 trials (Other 2, Observational 10, Not applicable 31, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 1 1) 2022: 82 trials (Observational 16, Not applicable 50, Phase 4 3, Phase 3 6, Phase 2 2, Phase 1/2 1, Phase 1 4) 2023: 97 trials (Observational 16, Not applicable 69, Phase 4 2, Phase 3 5, Phase 2 2, Phase 1 3) 2024: 84 trials (Observational 16, Not applicable 57, Phase 4 2, Phase 3 3, Phase 2 3, Phase 1/2 2, Phase 1 1) 2025: 83 trials (Observational 19, Not applicable 54, Phase 3 4, Phase 2/3 1, Phase 2 5)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 75
2025 83
2024 84
2023 97
2022 82
2021 47
2020 54
2019 53
2018 67
2017 38

Forecast of the full-year count, planned starts included, not rows of this table: about 94 trials starting in 2026 and about 86 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 110 trials still running at the 2026-10-09 snapshot; registered median of 7 months across 691 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Myopia trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 25
Phase 1/2 9
Phase 2 23
Phase 2/3 5
Phase 3 50
Phase 4 47
Not applicable 769
Observational 196
Unknown 4

How many Myopia trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 75
Recruiting 100
Enrolling by invitation 12
Active, not recruiting 76
Completed 671

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Myopia trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
CooperVision, Inc. 99
Alcon Research 75
Johnson & Johnson Vision Care, Inc. 43
CIBA VISION 39
Bausch & Lomb Incorporated 35

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Atropine 1% 19
Clear Care 9
0.01 atropine 7
Aceclidine ophthalmic solution 6
Aceclidine+Brimonidine combination ophthalmic solution 6

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Myopia trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Intraocular lens extraction 119 1
Corneal endothelial cell loss 99 1
Iris adhesions 88 1
Cataract nuclear 66 1
Intraocular lens implant 64 1

Which publications cover Myopia? (789)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages