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Condition (MeSH)

Occupational Diseases

ClinicalTrials.gov lists 705 trials for Occupational Diseases or a narrower condition beneath it. Vanda Pharmaceuticals has the most among industry and government lead sponsors, with 9.

MeSH D009784 Occupational Diseases C24
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Phase 1 Phase 1 25 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 17 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 22 Phase 4 Phase 4 12 Not applicable Not applicable 415 Observational Observational 208 Phase 1 Phase 1 25 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 17 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 22 Phase 4 Phase 4 12 Not applicable Not applicable 415 Observational Observational 208

Trials per phase (log scale)

47 of the 705 trials are tagged with Occupational Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Occupational Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Occupational Diseases trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 77

1999: 4 trials (Observational 1, Not applicable 1, Phase 3 2) 2000: 2 trials (Observational 1, Phase 2 1) 2001: 1 trials (Observational 1) 2003: 2 trials (Observational 1, Not applicable 1) 2004: 3 trials (Phase 3 2, Phase 2 1) 2005: 9 trials (Observational 2, Not applicable 5, Phase 2 1, Phase 1/2 1) 2006: 4 trials (Not applicable 3, Phase 2 1) 2007: 9 trials (Observational 4, Not applicable 3, Phase 2 1, Phase 1 1) 2008: 13 trials (Observational 5, Not applicable 2, Phase 4 3, Phase 2 1, Phase 1 2) 2009: 14 trials (Observational 4, Not applicable 7, Phase 1/2 1, Phase 1 2) 2010: 10 trials (Observational 3, Not applicable 2, Phase 3 3, Phase 1/2 2) 2011: 10 trials (Observational 5, Not applicable 3, Phase 3 2) 2012: 9 trials (Observational 1, Not applicable 6, Phase 3 1, Phase 2 1) 2013: 8 trials (Observational 1, Not applicable 7) 2014: 7 trials (Observational 1, Not applicable 3, Phase 4 2, Phase 1 1) 2015: 15 trials (Observational 4, Not applicable 9, Phase 3 2) 2016: 28 trials (Observational 4, Not applicable 16, Phase 4 2, Phase 3 1, Phase 2 1, Phase 1/2 1, Phase 1 3) 2017: 31 trials (Observational 8, Not applicable 21, Phase 4 1, Phase 1 1) 2018: 40 trials (Observational 12, Not applicable 26, Phase 3 1, Phase 2 1) 2019: 45 trials (Observational 11, Not applicable 32, Phase 3 1, Phase 2 1) 2020: 40 trials (Observational 20, Not applicable 15, Phase 3 1, Phase 2 1, Phase 1 3) 2021: 58 trials (Observational 15, Not applicable 39, Phase 2 1, Phase 1 3) 2022: 77 trials (Observational 31, Not applicable 39, Phase 4 2, Phase 3 3, Phase 1 2) 2023: 75 trials (Observational 19, Not applicable 51, Phase 4 2, Phase 2/3 1, Phase 1 2) 2024: 68 trials (Observational 12, Not applicable 49, Phase 3 3, Phase 2 3, Phase 1 1) 2025: 63 trials (Observational 21, Not applicable 38, Phase 2 2, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 54
2025 63
2024 68
2023 75
2022 77
2021 58
2020 40
2019 45
2018 40
2017 31

Forecast of the full-year count, planned starts included, not rows of this table: about 68 trials starting in 2026 and about 64 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 34 months from start to primary completion across 67 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 433 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Occupational Diseases trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 25
Phase 1/2 5
Phase 2 17
Phase 2/3 1
Phase 3 22
Phase 4 12
Not applicable 415
Observational 208

How many Occupational Diseases trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 52
Recruiting 62
Enrolling by invitation 10
Active, not recruiting 21
Completed 411

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Occupational Diseases trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Vanda Pharmaceuticals 9
US Department of Veterans Affairs 8

Which drugs are being tested for Occupational Diseases? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Tasimelteon 9

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Melatonin PR 12
Pirfenidoneone 3
Exercise 3
Treatment As Usual 3
Acupuncture 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Occupational Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Surgeries/Procedures 30 1
Hospital Admissions 8 1
Emergency Department Visits 7 1
Deaths 5 1
Accidents 3 1

Which publications cover Occupational Diseases? (1,105)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
The One-Minute Triple Stretch Reduces Musculoskeletal Discomfort in Endoscopic Assistants: A Crossover Trial With Motion Analysis. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2026 Yes
Ergonomics training with exercise and manual therapy in textile workers: a randomized controlled trial. International archives of occupational and environmental health 2025 Yes
Effectiveness of ergonomics training and exercise in tea workers: a randomized controlled trial. International archives of occupational and environmental health 2025 Yes
The effect of combined ergonomic training and exercises on musculoskeletal pain and ergonomic risks in supermarket cashiers: a randomized controlled trial. International archives of occupational and environmental health 2025 Yes
Low back pain and sitting time, posture and behavior in office workers: A scoping review. Journal of back and musculoskeletal rehabilitation 2025 Yes

Sub-conditions in MeSH (11)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages