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Condition (MeSH)

Pancreatic Diseases

ClinicalTrials.gov lists 6,430 trials for Pancreatic Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 128.

MeSH D010182 Digestive System Diseases C06
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Phase 1 Phase 1 980 Phase 1/2 Phase 1/2 458 Phase 2 Phase 2 1,158 Phase 2/3 Phase 2/3 80 Phase 3 Phase 3 392 Phase 4 Phase 4 209 Not applicable Not applicable 1,484 Observational Observational 1,642 Phase 1 Phase 1 980 Phase 1/2 Phase 1/2 458 Phase 2 Phase 2 1,158 Phase 2/3 Phase 2/3 80 Phase 3 Phase 3 392 Phase 4 Phase 4 209 Not applicable Not applicable 1,484 Observational Observational 1,642

Trials per phase (log scale)

1 more section with rows

183 of the 6,430 trials are tagged with Pancreatic Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Pancreatic Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Pancreatic Diseases trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 16 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 368

1990: 2 trials (Observational 2) 1991: 3 trials (Observational 2, Phase 2 1) 1992: 1 trials (Observational 1) 1993: 1 trials (Phase 1 1) 1994: 3 trials (Observational 1, Phase 2 1, Phase 1 1) 1995: 11 trials (Observational 1, Phase 3 1, Phase 2 4, Phase 1 5) 1996: 11 trials (Observational 3, Not applicable 2, Phase 3 1, Phase 2 4, Phase 1 1) 1997: 15 trials (Not applicable 2, Phase 3 2, Phase 2 3, Phase 1/2 2, Phase 1 6) 1998: 26 trials (Observational 2, Not applicable 1, Phase 3 3, Phase 2 6, Phase 1/2 1, Phase 1 13) 1999: 34 trials (Observational 4, Not applicable 3, Phase 4 1, Phase 3 2, Phase 2 20, Phase 1 4) 2000: 39 trials (Observational 9, Not applicable 1, Phase 3 4, Phase 2/3 3, Phase 2 9, Phase 1/2 2, Phase 1 11) 2001: 62 trials (Observational 11, Not applicable 6, Phase 4 5, Phase 3 12, Phase 2 14, Phase 1/2 5, Phase 1 9) 2002: 50 trials (Observational 7, Not applicable 1, Phase 4 3, Phase 3 5, Phase 2/3 2, Phase 2 20, Phase 1/2 2, Phase 1 10) 2003: 77 trials (Observational 3, Not applicable 8, Phase 4 4, Phase 3 8, Phase 2/3 4, Phase 2 37, Phase 1/2 7, Phase 1 6) 2004: 96 trials (Observational 22, Not applicable 7, Phase 4 3, Phase 3 9, Phase 2/3 3, Phase 2 27, Phase 1/2 8, Phase 1 17) 2005: 106 trials (Observational 11, Not applicable 10, Phase 4 4, Phase 3 12, Phase 2/3 4, Phase 2 41, Phase 1/2 7, Phase 1 17) 2006: 164 trials (Observational 29, Not applicable 22, Phase 4 6, Phase 3 19, Phase 2/3 2, Phase 2 48, Phase 1/2 9, Phase 1 29) 2007: 178 trials (Observational 35, Not applicable 23, Phase 4 10, Phase 3 22, Phase 2/3 2, Phase 2 45, Phase 1/2 11, Phase 1 30) 2008: 198 trials (Observational 44, Not applicable 30, Phase 4 12, Phase 3 20, Phase 2/3 1, Phase 2 45, Phase 1/2 15, Phase 1 31) 2009: 190 trials (Observational 34, Not applicable 34, Phase 4 9, Phase 3 19, Phase 2/3 1, Phase 2 39, Phase 1/2 16, Phase 1 38) 2010: 190 trials (Observational 48, Not applicable 37, Phase 4 13, Phase 3 17, Phase 2/3 2, Phase 2 38, Phase 1/2 8, Phase 1 27) 2011: 214 trials (Observational 48, Not applicable 50, Phase 4 6, Phase 3 11, Phase 2/3 1, Phase 2 46, Phase 1/2 12, Phase 1 40) 2012: 202 trials (Observational 41, Not applicable 56, Phase 4 13, Phase 3 13, Phase 2/3 2, Phase 2 37, Phase 1/2 14, Phase 1 26) 2013: 248 trials (Observational 64, Not applicable 58, Phase 4 11, Phase 3 15, Phase 2/3 2, Phase 2 35, Phase 1/2 17, Phase 1 46) 2014: 245 trials (Observational 67, Not applicable 61, Phase 4 8, Phase 3 18, Phase 2/3 4, Phase 2 36, Phase 1/2 11, Phase 1 40) 2015: 283 trials (Observational 74, Not applicable 66, Phase 4 6, Phase 3 23, Phase 2/3 6, Phase 2 44, Phase 1/2 18, Phase 1 46) 2016: 324 trials (Observational 66, Not applicable 102, Phase 4 18, Phase 3 12, Phase 2/3 2, Phase 2 52, Phase 1/2 24, Phase 1 48) 2017: 326 trials (Observational 88, Not applicable 79, Phase 4 7, Phase 3 16, Phase 2/3 2, Phase 2 60, Phase 1/2 25, Phase 1 49) 2018: 314 trials (Observational 96, Not applicable 80, Phase 4 10, Phase 3 21, Phase 2/3 4, Phase 2 38, Phase 1/2 30, Phase 1 35) 2019: 345 trials (Observational 109, Not applicable 96, Phase 4 6, Phase 3 10, Phase 2/3 2, Phase 2 59, Phase 1/2 22, Phase 1 41) 2020: 334 trials (Observational 104, Not applicable 93, Phase 4 12, Phase 3 12, Phase 2/3 4, Phase 2 47, Phase 1/2 21, Phase 1 41) 2021: 367 trials (Observational 124, Not applicable 96, Phase 4 5, Phase 3 13, Phase 2/3 4, Phase 2 46, Phase 1/2 27, Phase 1 52) 2022: 362 trials (Observational 109, Not applicable 108, Phase 4 5, Phase 3 10, Phase 2/3 2, Phase 2 43, Phase 1/2 28, Phase 1 57) 2023: 333 trials (Observational 99, Not applicable 87, Phase 4 11, Phase 3 10, Phase 2/3 2, Phase 2 45, Phase 1/2 23, Phase 1 56) 2024: 368 trials (Observational 105, Not applicable 81, Phase 4 4, Phase 3 13, Phase 2/3 7, Phase 2 67, Phase 1/2 31, Phase 1 60) 2025: 326 trials (Observational 91, Not applicable 84, Phase 4 8, Phase 3 18, Phase 2/3 8, Phase 2 52, Phase 1/2 24, Phase 1 41)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 308
2025 326
2024 368
2023 333
2022 362
2021 367
2020 334
2019 345
2018 314
2017 326

Forecast of the full-year count, planned starts included, not rows of this table: about 350 trials starting in 2026 and about 340 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 682 trials still running at the 2026-10-09 snapshot; registered median of 30 months across 3,727 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Pancreatic Diseases trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 980
Phase 1/2 458
Phase 2 1,158
Phase 2/3 80
Phase 3 392
Phase 4 209
Not applicable 1,484
Observational 1,642
Expanded access 27

How many Pancreatic Diseases trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 291
Recruiting 874
Enrolling by invitation 35
Active, not recruiting 306
Available 7

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Pancreatic Diseases trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 128
Vertex Pharmaceuticals Incorporated 118

Which drugs are being tested for Pancreatic Diseases? (9)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
NAB paclitaxel 200
OXALIPLATIN 116
"Capecitabine" 112
Calcium Leucovorin 82
Irinotecan 81

Interventions as named in the registry (6)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Gemcitabine/Gemzar 557
Fluorouracile 134
Radiation Therapy 74
Cisplatin 1 67
1- Erlotinib 59

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Pancreatic Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Infective pulmonary exacerbation of cystic fibrosis 2,530 96
Abdominal pain 1,023 198
Vomiting 957 220
Pyrexia 831 132
Nausea 774 193

Which publications cover Pancreatic Diseases? (266)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (8)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages