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Condition (MeSH)

Placenta Diseases

ClinicalTrials.gov lists 317 trials for Placenta Diseases or a narrower condition beneath it.

MeSH D010922 Urogenital Diseases C12
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Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 7 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 14 Phase 4 Phase 4 14 Not applicable Not applicable 122 Observational Observational 151 Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 7 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 14 Phase 4 Phase 4 14 Not applicable Not applicable 122 Observational Observational 151

Trials per phase (log scale)

27 of the 317 trials are tagged with Placenta Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Placenta Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Placenta Diseases trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 29

1997: 1 trials (Phase 3 1) 1999: 1 trials (Phase 2 1) 2000: 1 trials (Observational 1) 2002: 2 trials (Phase 4 1, Phase 1/2 1) 2003: 2 trials (Observational 2) 2004: 3 trials (Not applicable 2, Phase 2 1) 2005: 1 trials (Not applicable 1) 2006: 5 trials (Observational 2, Not applicable 2, Phase 1/2 1) 2008: 5 trials (Not applicable 1, Phase 4 1, Phase 2/3 1, Phase 2 1, Phase 1/2 1) 2009: 7 trials (Observational 2, Not applicable 3, Phase 3 1, Phase 2/3 1) 2010: 2 trials (Observational 2) 2011: 4 trials (Not applicable 2, Phase 4 1, Phase 1 1) 2012: 8 trials (Observational 2, Not applicable 2, Phase 3 2, Phase 2/3 1, Phase 2 1) 2013: 10 trials (Observational 5, Not applicable 3, Phase 4 1, Phase 3 1) 2014: 7 trials (Observational 1, Not applicable 4, Phase 4 2) 2015: 8 trials (Observational 6, Not applicable 2) 2016: 20 trials (Observational 9, Not applicable 6, Phase 4 3, Phase 3 1, Phase 2 1) 2017: 20 trials (Observational 13, Not applicable 5, Phase 4 1, Phase 3 1) 2018: 26 trials (Observational 7, Not applicable 16, Phase 3 2, Phase 2 1) 2019: 17 trials (Observational 10, Not applicable 6, Phase 2/3 1) 2020: 29 trials (Observational 16, Not applicable 11, Phase 3 1, Phase 2/3 1) 2021: 21 trials (Observational 11, Not applicable 9, Phase 3 1) 2022: 27 trials (Observational 17, Not applicable 8, Phase 4 2) 2023: 26 trials (Observational 15, Not applicable 10, Phase 3 1) 2024: 26 trials (Observational 13, Not applicable 12, Phase 4 1) 2025: 20 trials (Observational 9, Not applicable 10, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 17
2025 20
2024 26
2023 26
2022 27
2021 21
2020 29
2019 17
2018 26
2017 20

Forecast of the full-year count, planned starts included, not rows of this table: about 22 trials starting in 2026 and about 21 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 27 trials still running at the 2026-10-09 snapshot; registered median of 20 months across 162 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Placenta Diseases trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 1/2 3
Phase 2 7
Phase 2/3 5
Phase 3 14
Phase 4 14
Not applicable 122
Observational 151

How many Placenta Diseases trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 25
Recruiting 25
Enrolling by invitation 1
Active, not recruiting 2
Completed 150

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Placenta Diseases? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
MisoprostoL 4
LOVENOX 3

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
acid tranexamic 13
EC Aspirin 5
IM Oxytocin 5
Ampicillin + gentamicin 3
Topical TRanexamic Acid 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Placenta Diseases trials report? (9)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Adverse event 8 1
Culture Proven Sepsis 2 1
IVH 1-2 days of age 2 1
IVH 5-7 days of age 2 1
NEC within 30 days 2 1

Which publications cover Placenta Diseases? (87)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Early pregnancy imaging predicts ischemic placental disease. Placenta 2023 Yes
Development and validation of model for prediction of placental dysfunction-related stillbirth from maternal factors, fetal weight and uterine artery Doppler at mid-gestation. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2022 Yes
Doppler evaluation of normal and abnormal placenta. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2022 Yes
Acute and Chronic Placental Abnormalities in a Multicenter Cohort of Newborn Infants with Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2021 Yes
Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria. eLife 2021 Yes

Sub-conditions in MeSH (6)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, and rare-disease identity.

Browse all condition evidence pages