Condition (MeSH)
Proctocolitis
ClinicalTrials.gov lists 12 trials for Proctocolitis or a narrower condition beneath it. Bausch Health Americas, Inc. has the most among industry and government lead sponsors, with 3.
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Trials per phase
12 of the 12 trials are tagged with Proctocolitis itself; the rest are tagged with a narrower condition beneath it.
When did Proctocolitis trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 1 |
| 2021 | 1 |
| 2020 | 1 |
| 2015 | 1 |
| 2014 | 1 |
| 2011 | 1 |
| 2010 | 3 |
| 2009 | 3 |
No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 12 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Proctocolitis trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 4 |
| Not applicable | 2 |
| Observational | 5 |
How many Proctocolitis trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 8 |
| Terminated | 2 |
| Withdrawn | 1 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Proctocolitis trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Bausch Health Americas, Inc. | 3 |
| Forest Laboratories | 1 |
| NHS Grampian | 1 |
| PurGenesis Technologies Inc. | 1 |
Which drugs are being tested for Proctocolitis? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Aloe Vera Gel | 1 |
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Budesonide EC | 3 |
| PUR 0110 Rectal Enema 500 mg | 1 |
| PUR 0110 Rectal Enema 250 mg | 1 |
| MMX Mesalamine | 1 |
| PUR 0110 Rectal Enema 1000 mg | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Proctocolitis trials report? (9)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Colitis ulcerative | 2 | 2 |
| Abdominal pain | 1 | 1 |
| Acute generalised exanthematous pustulosis | 1 | 1 |
| Anaemia | 1 | 1 |
| Arterial thrombosis limb | 1 | 1 |
Showing 5 of 9 adverse events.
Which publications cover Proctocolitis? (8)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Can Faecal Zonulin and Calprotectin Levels Be Used in the Diagnosis and Follow-Up in Infants with Milk Protein-Induced Allergic Proctocolitis? | Nutrients | 2024 | Yes |
| Real-world evidence of quality of life improvement in patients with distal ulcerative colitis treated by mesalazine: the Quartz study. | European journal of gastroenterology & hepatology | 2022 | Yes |
| Budesonide foam induces remission in patients with mild to moderate ulcerative proctitis and ulcerative proctosigmoiditis. | Gastroenterology | 2015 | Yes |
| Prevention of acute radiation-induced proctosigmoiditis by balsalazide: a randomized, double-blind, placebo controlled trial in prostate cancer patients. | International journal of radiation oncology, biology, physics | 2005 | Yes |
| Natural history of late radiation proctosigmoiditis treated with topical sucralfate suspension. | Digestive diseases and sciences | 1999 | Yes |
Showing 5 of 8 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.