Condition (MeSH)
Pulmonary Valve Insufficiency
ClinicalTrials.gov lists 31 trials for Pulmonary Valve Insufficiency or a narrower condition beneath it. Edwards Lifesciences has the most among industry and government lead sponsors, with 8.
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Trials per phase
31 of the 31 trials are tagged with Pulmonary Valve Insufficiency itself; the rest are tagged with a narrower condition beneath it.
When did Pulmonary Valve Insufficiency trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 1 |
| 2023 | 1 |
| 2022 | 2 |
| 2021 | 2 |
| 2020 | 2 |
| 2019 | 2 |
| 2018 | 1 |
| 2017 | 3 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Pulmonary Valve Insufficiency trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2/3 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
| Not applicable | 18 |
| Observational | 10 |
How many Pulmonary Valve Insufficiency trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 7 |
| Active, not recruiting | 7 |
| Completed | 11 |
| Unknown status | 5 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Pulmonary Valve Insufficiency trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Edwards Lifesciences | 8 |
| Medtronic Cardiovascular | 2 |
| Taewoong Medical Co., Ltd. | 2 |
| Venus MedTech (HangZhou) Inc. | 2 |
| CryoLife, Inc. | 1 |
Showing 5 of 7 sponsors.
Interventions as named in the registry (1)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| SGLT2 Inhibitor | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Pulmonary Valve Insufficiency trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Other | 13 | 1 |
| Infection (excluding endocarditis) | 7 | 1 |
| Mortality | 7 | 1 |
| Reoperation/Reintervention | 7 | 1 |
| Arrhythmia | 6 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Pulmonary Valve Insufficiency? (51)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Midterm Outcomes in a Pooled Cohort of Harmony Transcatheter Pulmonary Valve Recipients. | Circulation. Cardiovascular interventions | 2025 | Yes |
| Novel size-adjustable pulmonary valve US early feasibility study: One-year outcomes. | The Journal of thoracic and cardiovascular surgery | 2025 | Yes |
| Outcomes of transcatheter pulmonary SAPIEN 3 valve implantation: an international registry. | European heart journal | 2024 | Yes |
| Congenital Pulmonic Valve Dysfunction Treated With SAPIEN 3 Transcatheter Heart Valve (from the COMPASSION S3 Trial). | The American journal of cardiology | 2023 | Yes |
| Systematic Electrophysiological Study Prior to Pulmonary Valve Replacement in Tetralogy of Fallot: A Prospective Multicenter Study. | Circulation. Arrhythmia and electrophysiology | 2023 | Yes |
Showing 5 of 51 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.