Condition (MeSH)
Scotoma
ClinicalTrials.gov lists 14 trials for Scotoma or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
14 of the 14 trials are tagged with Scotoma itself; the rest are tagged with a narrower condition beneath it.
When did Scotoma trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Not applicable
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 1 |
| 2023 | 2 |
| 2022 | 4 |
| 2017 | 1 |
| 2016 | 1 |
| 2013 | 2 |
| 2011 | 1 |
| 2007 | 2 |
No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Scotoma trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Phase 2 | 1 |
| Phase 3 | 2 |
| Not applicable | 9 |
How many Scotoma trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 3 |
| Active, not recruiting | 2 |
| Completed | 8 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Scotoma trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Alcon Research | 1 |
| Novartis Pharmaceuticals | 1 |
| VA Office of Research and Development | 1 |
Which drugs are being tested for Scotoma? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Ocriplasmin | 1 |
| Brolucizumab | 1 |
Interventions as named in the registry (2)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| SHAM injection | 1 |
| intravitreal injection Lucentis (ranibizumab) | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Scotoma trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Macular hole | 14 | 1 |
| Retinal detachment | 3 | 1 |
| Vitreous adhesions | 3 | 1 |
| Pneumonia | 2 | 1 |
| Angle closure glaucoma | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Scotoma? (67)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Effectiveness of Low Vision Rehabilitation Using Microperimetric Acoustic Biofeedback Training in Patients with Central Scotoma. | Current eye research | 2021 | Yes |
| Specificity of various cluster criteria used for the detection of glaucomatous visual field abnormalities. | The British journal of ophthalmology | 2020 | Yes |
| Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies. | International ophthalmology | 2020 | Yes |
| Does internal limiting membrane peeling during epiretinal membrane surgery induce microscotomas on microperimetry? Study protocol for PEELING, a randomized controlled clinical trial. | Trials | 2020 | Yes |
| Accuracy of kinetic perimetry assessment with the Humphrey 850; an exploratory comparative study. | Eye (London, England) | 2019 | Yes |
Showing 5 of 67 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.