Condition (MeSH)
Spinal Cord Compression
ClinicalTrials.gov lists 46 trials for Spinal Cord Compression or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
46 of the 46 trials are tagged with Spinal Cord Compression itself; the rest are tagged with a narrower condition beneath it.
When did Spinal Cord Compression trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 3 |
| 2024 | 1 |
| 2023 | 3 |
| 2022 | 3 |
| 2021 | 2 |
| 2019 | 2 |
| 2018 | 3 |
| 2017 | 2 |
| 2016 | 4 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 2.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Spinal Cord Compression trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 4 |
| Phase 2/3 | 1 |
| Phase 3 | 3 |
| Not applicable | 20 |
| Observational | 14 |
How many Spinal Cord Compression trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 6 |
| Recruiting | 7 |
| Active, not recruiting | 2 |
| Completed | 18 |
| Terminated | 6 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Spinal Cord Compression trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Amgen | 2 |
| Cancer Trials Ireland | 2 |
Which drugs are being tested for Spinal Cord Compression? (6)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| DENOSUMAB | 2 |
| Laronidase | 2 |
| Magnesium Pantoprazole | 1 |
| Testosterone Cypionate | 1 |
| NAB paclitaxel | 1 |
Showing 5 of 6 drugs.
Interventions as named in the registry (8)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Radiation Therapy | 3 |
| Stereotactic body radiotherapy (SBRT) | 3 |
| Stereotactic Body Radiation Therapy | 2 |
| acid Zoledronic | 2 |
| Glucocorticoids | 1 |
Showing 5 of 8 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Spinal Cord Compression trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 323 | 3 |
| Malignant neoplasm progression | 204 | 2 |
| Dyspnoea | 128 | 2 |
| Anaemia | 125 | 2 |
| Febrile neutropenia | 113 | 2 |
Showing 5 of 10 adverse events.
Which publications cover Spinal Cord Compression? (199)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Obstacles to receiving postoperative radiation therapy following separation surgery for metastatic spine disease. | Journal of neurosurgery. Spine | 2024 | Yes |
| Efficacy and toxicity of primary re-irradiation for malignant spinal cord compression based on radiobiological modelling: a phase II clinical trial. | British journal of cancer | 2023 | Yes |
| Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial. | The Lancet. Neurology | 2021 | Yes |
| Comparison of 5 × 5 Gy and 10 × 3 Gy for metastatic spinal cord compression using data from three prospective trials. | Radiation oncology (London, England) | 2021 | Yes |
| Feasibility of salvage decompressive surgery for pending paralysis due to metastatic spinal cord compression. | Clinical neurology and neurosurgery | 2021 | Yes |
Showing 5 of 199 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.