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Condition (MeSH)

Thrombocytopenia

ClinicalTrials.gov lists 1,005 trials for Thrombocytopenia or a narrower condition beneath it. GlaxoSmithKline has the most among industry and government lead sponsors, with 28.

MeSH D013921 Hemic and Lymphatic Diseases C15
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Phase 1 Phase 1 81 Phase 1/2 Phase 1/2 45 Phase 2 Phase 2 270 Phase 2/3 Phase 2/3 32 Phase 3 Phase 3 171 Phase 4 Phase 4 55 Not applicable Not applicable 83 Observational Observational 262 Phase 1 Phase 1 81 Phase 1/2 Phase 1/2 45 Phase 2 Phase 2 270 Phase 2/3 Phase 2/3 32 Phase 3 Phase 3 171 Phase 4 Phase 4 55 Not applicable Not applicable 83 Observational Observational 262

Trials per phase

1 more section with rows

407 of the 1,005 trials are tagged with Thrombocytopenia itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Thrombocytopenia trials start? (34)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 3 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 85

1993: 1 trials (Observational 1) 1994: 1 trials (Phase 2 1) 1995: 2 trials (Not applicable 1, Phase 2 1) 1996: 2 trials (Observational 1, Phase 1 1) 1997: 2 trials (Phase 3 1, Phase 1 1) 1998: 2 trials (Phase 1/2 1, Phase 1 1) 1999: 3 trials (Phase 3 1, Phase 2 2) 2000: 6 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1, Phase 1/2 2) 2001: 5 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1, Phase 1 1) 2002: 9 trials (Observational 2, Phase 3 3, Phase 2 3, Phase 1/2 1) 2003: 13 trials (Observational 1, Phase 4 1, Phase 3 4, Phase 2/3 1, Phase 2 5, Phase 1/2 1) 2004: 8 trials (Not applicable 1, Phase 3 4, Phase 2 2, Phase 1 1) 2005: 26 trials (Observational 6, Not applicable 1, Phase 4 1, Phase 3 7, Phase 2 6, Phase 1/2 3, Phase 1 2) 2006: 23 trials (Observational 6, Phase 3 5, Phase 2/3 1, Phase 2 7, Phase 1/2 1, Phase 1 3) 2007: 25 trials (Observational 4, Not applicable 2, Phase 3 6, Phase 2 7, Phase 1/2 3, Phase 1 3) 2008: 23 trials (Observational 5, Phase 3 5, Phase 2/3 2, Phase 2 9, Phase 1/2 1, Phase 1 1) 2009: 29 trials (Observational 6, Not applicable 2, Phase 4 3, Phase 3 4, Phase 2 11, Phase 1/2 1, Phase 1 2) 2010: 36 trials (Observational 12, Not applicable 2, Phase 4 3, Phase 3 1, Phase 2/3 1, Phase 2 15, Phase 1/2 1, Phase 1 1) 2011: 29 trials (Observational 12, Not applicable 1, Phase 4 1, Phase 3 4, Phase 2 5, Phase 1/2 1, Phase 1 5) 2012: 40 trials (Observational 10, Not applicable 4, Phase 4 3, Phase 3 9, Phase 2/3 1, Phase 2 9, Phase 1/2 2, Phase 1 2) 2013: 31 trials (Observational 11, Not applicable 2, Phase 4 2, Phase 3 5, Phase 2/3 2, Phase 2 6, Phase 1 3) 2014: 39 trials (Observational 7, Not applicable 1, Phase 4 1, Phase 3 13, Phase 2/3 2, Phase 2 10, Phase 1/2 2, Phase 1 3) 2015: 35 trials (Observational 8, Not applicable 1, Phase 4 5, Phase 3 10, Phase 2/3 1, Phase 2 6, Phase 1/2 4) 2016: 30 trials (Observational 10, Not applicable 1, Phase 4 1, Phase 3 8, Phase 2/3 1, Phase 2 6, Phase 1/2 1, Phase 1 2) 2017: 39 trials (Observational 12, Not applicable 5, Phase 4 3, Phase 3 8, Phase 2 8, Phase 1 3) 2018: 47 trials (Observational 19, Not applicable 4, Phase 4 1, Phase 3 8, Phase 2/3 3, Phase 2 7, Phase 1/2 2, Phase 1 3) 2019: 51 trials (Observational 19, Not applicable 5, Phase 4 5, Phase 3 5, Phase 2/3 3, Phase 2 12, Phase 1/2 1, Phase 1 1) 2020: 44 trials (Observational 8, Not applicable 5, Phase 4 5, Phase 3 9, Phase 2 14, Phase 1 3) 2021: 67 trials (Observational 20, Not applicable 3, Phase 4 6, Phase 3 14, Phase 2/3 2, Phase 2 18, Phase 1/2 2, Phase 1 2) 2022: 60 trials (Observational 14, Not applicable 4, Phase 4 6, Phase 3 10, Phase 2/3 3, Phase 2 20, Phase 1 3) 2023: 66 trials (Observational 17, Not applicable 8, Phase 4 2, Phase 3 5, Phase 2/3 2, Phase 2 26, Phase 1/2 2, Phase 1 4) 2024: 58 trials (Observational 19, Not applicable 8, Phase 4 1, Phase 3 5, Phase 2/3 2, Phase 2 13, Phase 1/2 1, Phase 1 9) 2025: 85 trials (Observational 18, Not applicable 9, Phase 4 4, Phase 3 11, Phase 2/3 3, Phase 2 20, Phase 1/2 9, Phase 1 11)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 56
2025 85
2024 58
2023 66
2022 60
2021 67
2020 44
2019 51
2018 47
2017 39

Forecast of the full-year count, planned starts included, not rows of this table: about 75 trials starting in 2026 and about 79 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 121 trials still running at the 2026-10-09 snapshot; registered median of 28 months across 538 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Thrombocytopenia trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 81
Phase 1/2 45
Phase 2 270
Phase 2/3 32
Phase 3 171
Phase 4 55
Not applicable 83
Observational 262
Expanded access 6

How many Thrombocytopenia trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 57
Recruiting 159
Enrolling by invitation 4
Active, not recruiting 28
Available 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Thrombocytopenia trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
GlaxoSmithKline 28
Amgen 26
Novartis Pharmaceuticals 24
Alexion Pharmaceuticals, Inc. 21
National Heart, Lung, and Blood Institute (NHLBI) 18

Which drugs are being tested for Thrombocytopenia? (11)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Eltrombopag 84
Romiplostim 51
Avatrombopag 38
RITUXIMAB 32
Eculizumab 15

Interventions as named in the registry (4)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Dexamethasone/Dexamethasone acetate 42
rhTPO 16
Cyclosporine 0.05% 10
Platelet Transfusion 10

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Thrombocytopenia trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Febrile neutropenia 289 29
Pneumonia 279 54
Thrombocytopenia 214 57
Haemorrhage 154 13
Sepsis 152 45

Which publications cover Thrombocytopenia? (952)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (4)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages