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Condition (MeSH)

Vulvitis

ClinicalTrials.gov lists 132 trials for Vulvitis or a narrower condition beneath it. Scynexis, Inc. has the most among industry and government lead sponsors, with 8.

MeSH D014847 Urogenital Diseases C12
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Phase 1 Phase 1 11 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 17 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 23 Phase 4 Phase 4 9 Not applicable Not applicable 44 Observational Observational 19 Phase 1 Phase 1 11 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 17 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 23 Phase 4 Phase 4 9 Not applicable Not applicable 44 Observational Observational 19

Trials per phase

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When did Vulvitis trials start? (26)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 11

1995: 1 trials (Phase 1/2 1) 2000: 1 trials (Not applicable 1) 2002: 2 trials (Not applicable 2) 2004: 4 trials (Observational 1, Phase 4 1, Phase 3 2) 2005: 1 trials (Phase 4 1) 2006: 2 trials (Observational 1, Phase 2 1) 2007: 2 trials (Phase 1 2) 2008: 3 trials (Not applicable 1, Phase 3 2) 2009: 3 trials (Not applicable 2, Phase 2 1) 2010: 4 trials (Observational 1, Phase 3 1, Phase 2 1, Phase 1 1) 2011: 5 trials (Not applicable 3, Phase 2 2) 2012: 2 trials (Not applicable 1, Phase 1 1) 2013: 8 trials (Observational 1, Phase 4 2, Phase 3 1, Phase 2 1, Phase 1/2 1, Phase 1 2) 2014: 5 trials (Observational 1, Not applicable 1, Phase 4 2, Phase 3 1) 2015: 5 trials (Phase 3 1, Phase 2 3, Phase 1 1) 2016: 7 trials (Observational 2, Not applicable 2, Phase 2 3) 2017: 4 trials (Not applicable 1, Phase 3 1, Phase 2/3 1, Phase 2 1) 2018: 9 trials (Observational 1, Not applicable 3, Phase 3 4, Phase 1/2 1) 2019: 11 trials (Not applicable 4, Phase 4 1, Phase 3 4, Phase 2/3 1, Phase 2 1) 2020: 5 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 3 1) 2021: 9 trials (Observational 3, Not applicable 3, Phase 4 1, Phase 3 1, Phase 1 1) 2022: 11 trials (Observational 2, Not applicable 4, Phase 3 3, Phase 2 2) 2023: 8 trials (Not applicable 5, Phase 1/2 1, Phase 1 2) 2024: 8 trials (Observational 2, Not applicable 2, Phase 2/3 2, Phase 1/2 1, Phase 1 1) 2025: 6 trials (Observational 2, Not applicable 3, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 6
2025 6
2024 8
2023 8
2022 11
2021 9
2020 5
2019 11
2018 9
2017 4

Forecast of the full-year count, planned starts included, not rows of this table: about 8 trials starting in 2026 and about 7 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 27 months from start to primary completion across 13 trials still running at the 2026-10-09 snapshot; registered median of 13 months across 91 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Vulvitis trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 11
Phase 1/2 5
Phase 2 17
Phase 2/3 4
Phase 3 23
Phase 4 9
Not applicable 44
Observational 19

How many Vulvitis trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Recruiting 12
Active, not recruiting 5
Completed 86
Terminated 7

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Vulvitis trials? (12)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Scynexis, Inc. 8
Gedea Biotech AB 5
Bayer 3
Mycovia Pharmaceuticals Inc. 3
National Institute of Allergy and Infectious Diseases (NIAID) 3

Which drugs are being tested for Vulvitis? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
IBREXAFUNGERP 8
Clotrimazole 6
VT-1161 6
Butoconazole nitrate 2

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Fluconazol 17
Terconazole Vaginal Suppository 3
Acupuncture 2
Gynomax® XL Vaginal Ovule 2
Clotrimazole vaginal tablet 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Vulvitis trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Acute kidney injury 7 1
COVID-19 6 2
Diarrhoea 6 1
Pneumonia 6 3
Respiratory failure 6 1

Which publications cover Vulvitis? (18)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
A histologic review of vulvar inflammatory dermatoses and intraepithelial neoplasm. Dermatologic clinics 2010 Yes
Re: vulvar vestibulitis may be a referred pain arising from laxity in the uterosacral ligaments: a hypothesis based on three prospective case reports. The Australian & New Zealand journal of obstetrics & gynaecology 2004 Yes
The unconsummated marriage: causes and management. Clinical and experimental obstetrics & gynecology 2004 Yes
Increased innervation of the vulval vestibule in patients with vulvodynia. The British journal of dermatology 2003 Yes
Estrogen receptor expression in vulvar vestibulitis syndrome. American journal of obstetrics and gynecology 2003 Yes

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages