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Condition (MeSH)

Inflammatory Bowel Diseases

ClinicalTrials.gov lists 3,800 trials for Inflammatory Bowel Diseases or a narrower condition beneath it. Takeda has the most among industry and government lead sponsors, with 80.

MeSH D015212 Digestive System Diseases C06
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Phase 1 Phase 1 286 Phase 1/2 Phase 1/2 106 Phase 2 Phase 2 492 Phase 2/3 Phase 2/3 65 Phase 3 Phase 3 394 Phase 4 Phase 4 267 Not applicable Not applicable 950 Observational Observational 1,232 Phase 1 Phase 1 286 Phase 1/2 Phase 1/2 106 Phase 2 Phase 2 492 Phase 2/3 Phase 2/3 65 Phase 3 Phase 3 394 Phase 4 Phase 4 267 Not applicable Not applicable 950 Observational Observational 1,232

Trials per phase

1 more section with rows

1,544 of the 3,800 trials are tagged with Inflammatory Bowel Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Inflammatory Bowel Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Inflammatory Bowel Diseases trials start? (32)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 9 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 252

1990: 1 trials (Observational 1) 1995: 4 trials (Observational 2, Not applicable 1, Phase 2/3 1) 1996: 4 trials (Observational 1, Phase 3 2, Phase 2 1) 1998: 2 trials (Observational 2) 1999: 2 trials (Observational 2) 2000: 10 trials (Observational 3, Not applicable 1, Phase 3 4, Phase 2 1, Phase 1 1) 2001: 13 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 3 3, Phase 2/3 1, Phase 2 3, Phase 1 2) 2002: 36 trials (Observational 6, Not applicable 1, Phase 4 1, Phase 3 10, Phase 2/3 2, Phase 2 15, Phase 1/2 1) 2003: 37 trials (Observational 8, Not applicable 1, Phase 4 3, Phase 3 13, Phase 2/3 1, Phase 2 10, Phase 1 1) 2004: 46 trials (Observational 9, Not applicable 7, Phase 4 2, Phase 3 16, Phase 2/3 1, Phase 2 6, Phase 1/2 3, Phase 1 2) 2005: 53 trials (Observational 9, Not applicable 4, Phase 4 8, Phase 3 13, Phase 2/3 2, Phase 2 12, Phase 1/2 2, Phase 1 3) 2006: 78 trials (Observational 11, Not applicable 12, Phase 3 24, Phase 2/3 2, Phase 2 20, Phase 1/2 5, Phase 1 4) 2007: 90 trials (Observational 26, Not applicable 16, Phase 4 6, Phase 3 20, Phase 2/3 5, Phase 2 13, Phase 1/2 1, Phase 1 3) 2008: 84 trials (Observational 15, Not applicable 16, Phase 4 11, Phase 3 18, Phase 2/3 1, Phase 2 16, Phase 1/2 4, Phase 1 3) 2009: 96 trials (Observational 32, Not applicable 17, Phase 4 6, Phase 3 19, Phase 2/3 1, Phase 2 10, Phase 1/2 4, Phase 1 7) 2010: 93 trials (Observational 33, Not applicable 16, Phase 4 8, Phase 3 6, Phase 2/3 1, Phase 2 10, Phase 1/2 8, Phase 1 11) 2011: 110 trials (Observational 37, Not applicable 11, Phase 4 9, Phase 3 17, Phase 2/3 1, Phase 2 24, Phase 1/2 3, Phase 1 8) 2012: 138 trials (Observational 44, Not applicable 25, Phase 4 10, Phase 3 19, Phase 2 25, Phase 1/2 4, Phase 1 11) 2013: 130 trials (Observational 37, Not applicable 32, Phase 4 12, Phase 3 8, Phase 2/3 2, Phase 2 18, Phase 1/2 6, Phase 1 15) 2014: 162 trials (Observational 50, Not applicable 43, Phase 4 12, Phase 3 23, Phase 2/3 1, Phase 2 15, Phase 1/2 6, Phase 1 12) 2015: 175 trials (Observational 53, Not applicable 44, Phase 4 18, Phase 3 14, Phase 2/3 3, Phase 2 21, Phase 1/2 9, Phase 1 13) 2016: 183 trials (Observational 52, Not applicable 50, Phase 4 22, Phase 3 17, Phase 2/3 2, Phase 2 22, Phase 1/2 3, Phase 1 15) 2017: 193 trials (Observational 61, Not applicable 57, Phase 4 15, Phase 3 18, Phase 2/3 2, Phase 2 19, Phase 1/2 6, Phase 1 15) 2018: 196 trials (Observational 61, Not applicable 50, Phase 4 11, Phase 3 25, Phase 2/3 5, Phase 2 26, Phase 1/2 2, Phase 1 16) 2019: 219 trials (Observational 82, Not applicable 67, Phase 4 13, Phase 3 9, Phase 2/3 7, Phase 2 21, Phase 1/2 6, Phase 1 14) 2020: 204 trials (Observational 83, Not applicable 48, Phase 4 7, Phase 3 15, Phase 2/3 4, Phase 2 22, Phase 1/2 5, Phase 1 20) 2021: 230 trials (Observational 85, Not applicable 65, Phase 4 14, Phase 3 19, Phase 2/3 1, Phase 2 27, Phase 1/2 1, Phase 1 18) 2022: 225 trials (Observational 83, Not applicable 67, Phase 4 14, Phase 3 9, Phase 2/3 5, Phase 2 22, Phase 1/2 7, Phase 1 18) 2023: 225 trials (Observational 82, Not applicable 64, Phase 4 13, Phase 3 15, Phase 2/3 6, Phase 2 25, Phase 1/2 3, Phase 1 17) 2024: 247 trials (Observational 92, Not applicable 79, Phase 4 13, Phase 3 14, Phase 2/3 3, Phase 2 23, Phase 1/2 5, Phase 1 18) 2025: 252 trials (Observational 92, Not applicable 83, Phase 4 13, Phase 3 15, Phase 2/3 2, Phase 2 28, Phase 1/2 5, Phase 1 14)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 232
2025 252
2024 247
2023 225
2022 225
2021 230
2020 204
2019 219
2018 196
2017 193

Forecast of the full-year count, planned starts included, not rows of this table: about 270 trials starting in 2026 and about 260 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 361 trials still running at the 2026-10-09 snapshot; registered median of 27 months across 2,165 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Inflammatory Bowel Diseases trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 286
Phase 1/2 106
Phase 2 492
Phase 2/3 65
Phase 3 394
Phase 4 267
Not applicable 950
Observational 1,232
Expanded access 8

How many Inflammatory Bowel Diseases trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 204
Recruiting 535
Enrolling by invitation 34
Active, not recruiting 150
Available 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Inflammatory Bowel Diseases trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Takeda 80
AbbVie 74
Pfizer 52
Janssen Research & Development, LLC 45
Ferring Pharmaceuticals 29

Which drugs are being tested for Inflammatory Bowel Diseases? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
INFLIXIMAB 109
Certolizumab 31
(CP-6890,550) Tofacitinib 20
Ozanimod 20

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Adalimumab-US 84
Vedolizumab IV 83
MMX Mesalamine 70
Ustekinumab SC 53
Fecal Microbiota Transplantation 41

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Inflammatory Bowel Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Crohn's disease 2,589 112
CROHN'S DISEASE 1,569 29
Colitis ulcerative 1,544 127
Colitis Ulcerative 741 19
Small intestinal obstruction 476 70

Which publications cover Inflammatory Bowel Diseases? (1,633)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages