Condition (MeSH)
Corneal Edema
ClinicalTrials.gov lists 38 trials for Corneal Edema or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
38 of the 38 trials are tagged with Corneal Edema itself; the rest are tagged with a narrower condition beneath it.
When did Corneal Edema trials start? (14)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2025 | 4 |
| 2024 | 4 |
| 2023 | 4 |
| 2022 | 3 |
| 2021 | 5 |
| 2020 | 2 |
| 2019 | 2 |
| 2016 | 2 |
| 2015 | 1 |
Showing 10 of 14 earlier years.
No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 24 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 13 months across 24 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Corneal Edema trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 5 |
| Phase 1/2 | 1 |
| Phase 2 | 3 |
| Phase 2/3 | 1 |
| Phase 3 | 3 |
| Phase 4 | 6 |
| Not applicable | 11 |
| Observational | 8 |
How many Corneal Edema trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 5 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 3 |
| Completed | 24 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Corneal Edema trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Aurion Biotech | 4 |
| Eye-yon Medical | 4 |
| Alcon Research | 2 |
| Emmecell | 2 |
| Aerie Pharmaceuticals | 1 |
Showing 5 of 6 sponsors.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Dextenza 0.4Mg Ophthalmic Insert | 3 |
| Prednisolone Acetate 1% Oph Susp | 2 |
| EO2002 | 2 |
| Prednisolone 1% | 2 |
| Difluprednate Ophthalmic Emulsion 0.05% | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Corneal Edema trials report? (3)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Femur fracture | 1 | 1 |
| Hip fracture | 1 | 1 |
| Viral gastroenteritis | 1 | 1 |
Which publications cover Corneal Edema? (54)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Surgical Considerations for the Human Implantation of the Gore Synthetic Corneal Device. | Cornea | 2025 | Yes |
| Severe Corneal Flattening After Endothelial Keratoplasty: Collagen Compaction Syndrome. | Cornea | 2024 | Yes |
| Assessing Corneal Tomographic Changes in Fuchs Endothelial Corneal Dystrophy Over 1 Year: Scheimpflug Versus Anterior Segment Optical Coherence Tomography. | Cornea | 2024 | Yes |
| Safety of office-based lens surgery: U.S. multicenter study. | Journal of cataract and refractive surgery | 2023 | Yes |
| Phase 2, Randomized, Open-Label Parallel-Group Study of Two Dosing Regimens of Netarsudil for the Treatment of Corneal Edema Due to Fuchs Corneal Dystrophy. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics | 2022 | Yes |
Showing 5 of 54 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.