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Condition (MeSH)

Oligohydramnios

ClinicalTrials.gov lists 24 trials for Oligohydramnios or a narrower condition beneath it.

MeSH D016104 Urogenital Diseases C12
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Phase 1 Phase 1 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 2 Not applicable Not applicable 8 Observational Observational 8 Phase 1 Phase 1 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 2 Not applicable Not applicable 8 Observational Observational 8

Trials per phase

24 of the 24 trials are tagged with Oligohydramnios itself; the rest are tagged with a narrower condition beneath it.

Get the Oligohydramnios report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Oligohydramnios trials start? (16)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 3

2006: 1 trials (Not applicable 1) 2008: 1 trials (Phase 3 1) 2009: 1 trials (Phase 4 1) 2011: 1 trials (Phase 1 1) 2012: 1 trials (Not applicable 1) 2013: 3 trials (Observational 2, Phase 2/3 1) 2015: 1 trials (Phase 4 1) 2016: 1 trials (Observational 1) 2017: 1 trials (Observational 1) 2018: 1 trials (Not applicable 1) 2019: 2 trials (Observational 1, Not applicable 1) 2020: 2 trials (Observational 2) 2021: 2 trials (Observational 1, Not applicable 1) 2022: 3 trials (Not applicable 2, Phase 3 1) 2023: 1 trials (Phase 3 1) 2024: 2 trials (Not applicable 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2024 2
2023 1
2022 3
2021 2
2020 2
2019 2
2018 1
2017 1
2016 1
2015 1

No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Oligohydramnios trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 2 1
Phase 2/3 1
Phase 3 3
Phase 4 2
Not applicable 8
Observational 8

How many Oligohydramnios trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 4
Active, not recruiting 1
Completed 9
Terminated 2
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Oligohydramnios trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Kayseri Education and Research Hospital 2
Otsuka Pharmaceutical Development & Commercialization, Inc. 2
Antalya Training and Research Hospital 1
Deepecho 1
Hillel Yaffe Medical Center 1

Which drugs are being tested for Oligohydramnios? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
MisoprostoL 1
SILDENAFIL 1
Isosorbide Mononitrate 1

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Tolvaptan IR 2
IV/Oral Hydration and Bedrest 1
Warfarin VKA 1
anti oxidant omega 3 1
low sodium diet 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Oligohydramnios? (51)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Neonatal Survival After Serial Amnioinfusions for Bilateral Renal Agenesis: The Renal Anhydramnios Fetal Therapy Trial. JAMA 2023 Yes
NAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Yes
Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group. Nature reviews. Urology 2022 Yes
Design and Protocol of the Renal Anhydramnios Fetal Therapy (RAFT) Trial. Clinical therapeutics 2022 Yes
Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries. Reproductive health 2020 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages