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Condition (MeSH)

Spina Bifida Cystica

ClinicalTrials.gov lists 6 trials for Spina Bifida Cystica or a narrower condition beneath it.

MeSH D016137 Nervous System Diseases C10 C16 Listed by Orphanet as a rare disease
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Not applicable Not applicable 4 Observational Observational 2 Not applicable Not applicable 4 Observational Observational 2

Trials per phase

6 of the 6 trials are tagged with Spina Bifida Cystica itself; the rest are tagged with a narrower condition beneath it.

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When did Spina Bifida Cystica trials start? (4)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Not applicable
  • Observational

Top of scale: 2

2012: 1 trials (Observational 1) 2015: 1 trials (Not applicable 1) 2017: 2 trials (Observational 1, Not applicable 1) 2025: 2 trials (Not applicable 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 2
2017 2
2015 1
2012 1

No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 6 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Spina Bifida Cystica trials in? (2)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Not applicable 4
Observational 2

How many Spina Bifida Cystica trials are recruiting? (4)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Completed 2
Terminated 1
Unknown status 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which publications cover Spina Bifida Cystica? (12)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Improving motor function in fetal surgery for open spina bifida. BJOG : an international journal of obstetrics and gynaecology 2024 Yes
Patient empowerment improves follow-up data collection after fetal surgery for spina bifida: institutional audit. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2023 Yes
Laparotomy-Assisted 2-Port Fetoscopic Repair of Spina Bifida Aperta: Report of a Single-Center Experience in Paris, France. Fetal diagnosis and therapy 2022 Yes
Percutaneous minimal-access fetoscopic surgery for spina bifida aperta. Part II: maternal management and outcome. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2014 Yes
Percutaneous minimally invasive fetoscopic surgery for spina bifida aperta. Part I: surgical technique and perioperative outcome. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2014 Yes

Prevalence (6)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Spinal dysraphism with a posterior meningocele Prevalence at birth 1-5 / 10 000 Saudi Arabia Not stated Exact
Spinal dysraphism with a posterior meningocele Point prevalence Unknown Worldwide Not stated Unspecified
Spinal dysraphism with a posterior meningocele Point prevalence Unknown Worldwide Not stated Exact
Spinal dysraphism with a posterior meningocele Point prevalence Unknown Worldwide Not stated Exact
Spinal dysraphism with a posterior meningocele Prevalence at birth 1-5 / 10 000 Saudi Arabia Not stated Unspecified

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Spinal dysraphism with a posterior meningocele 268744 Exact Orphadata Science knowledge files, Product 1
Spinal dysraphism with a posterior meningocele 268744 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, and sub-conditions in mesh.

Not computed for conditions with fewer than 10 trials: drugs tested.

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