Condition (MeSH)
POEMS Syndrome
ClinicalTrials.gov lists 16 trials for POEMS Syndrome or a narrower condition beneath it. Novatim Immune Therapeutics (Zhejiang) Co., Ltd. has the most among industry and government lead sponsors, with 1.
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Trials per phase
16 of the 16 trials are tagged with POEMS Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did POEMS Syndrome trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 1 |
| 2023 | 1 |
| 2022 | 1 |
| 2021 | 2 |
| 2020 | 2 |
| 2018 | 1 |
| 2016 | 1 |
| 2014 | 2 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are POEMS Syndrome trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 7 |
| Observational | 5 |
How many POEMS Syndrome trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 6 |
| Active, not recruiting | 1 |
| Completed | 5 |
| Unknown status | 3 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most POEMS Syndrome trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Novatim Immune Therapeutics (Zhejiang) Co., Ltd. | 1 |
Which drugs are being tested for POEMS Syndrome? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| IXAZOMIB | 1 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Lenalidomide & Dexamethasone | 2 |
| Lenalidomide+Dexamethasone | 2 |
| Cyclophosphamide and Fludarabine | 1 |
| CT103A cells | 1 |
| CD19- BCMA CAR-T cells | 1 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do POEMS Syndrome trials report? (3)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Allergic rhinitis | 1 | 1 |
| Chills | 1 | 1 |
| Thromboembolic event | 1 | 1 |
Which publications cover POEMS Syndrome? (6)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 6 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| POEMS syndrome | Point prevalence | Unknown | Europe | Not stated | Exact |
| POEMS syndrome | Point prevalence | 1-9 / 1 000 000 | Japan | Not stated | Exact |
| POEMS syndrome | Point prevalence | 1-9 / 1 000 000 | Japan | Not stated | Unspecified |
| POEMS syndrome | Point prevalence | 1-9 / 1 000 000 | Japan | Not stated | Exact |
| POEMS syndrome | Point prevalence | Unknown | Europe | Not stated | Unspecified |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| POEMS syndrome | 2905 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| POEMS syndrome | 2905 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.