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Condition (MeSH)

Glucose Intolerance

ClinicalTrials.gov lists 784 trials for Glucose Intolerance or a narrower condition beneath it.

MeSH D018149 Nutritional and Metabolic Diseases C18
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Phase 1 Phase 1 24 Phase 1/2 Phase 1/2 9 Phase 2 Phase 2 58 Phase 2/3 Phase 2/3 7 Phase 3 Phase 3 32 Phase 4 Phase 4 61 Not applicable Not applicable 483 Observational Observational 110 Phase 1 Phase 1 24 Phase 1/2 Phase 1/2 9 Phase 2 Phase 2 58 Phase 2/3 Phase 2/3 7 Phase 3 Phase 3 32 Phase 4 Phase 4 61 Not applicable Not applicable 483 Observational Observational 110

Trials per phase (log scale)

784 of the 784 trials are tagged with Glucose Intolerance itself; the rest are tagged with a narrower condition beneath it.

Get the Glucose Intolerance report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Glucose Intolerance trials start? (33)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 49

1993: 1 trials (Not applicable 1) 1994: 1 trials (Not applicable 1) 1996: 1 trials (Phase 3 1) 1997: 1 trials (Observational 1) 1998: 1 trials (Phase 3 1) 1999: 1 trials (Not applicable 1) 2000: 2 trials (Observational 1, Phase 3 1) 2001: 5 trials (Observational 2, Phase 3 2, Phase 1 1) 2002: 6 trials (Observational 1, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 1 1) 2003: 10 trials (Observational 3, Not applicable 1, Phase 4 2, Phase 3 2, Phase 2 1, Phase 1 1) 2004: 14 trials (Not applicable 4, Phase 4 3, Phase 3 3, Phase 2 4) 2005: 16 trials (Observational 3, Not applicable 5, Phase 4 2, Phase 3 5, Phase 2 1) 2006: 22 trials (Observational 3, Not applicable 7, Phase 4 6, Phase 3 3, Phase 2/3 1, Phase 2 1, Phase 1 1) 2007: 27 trials (Observational 5, Not applicable 11, Phase 4 4, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1/2 1, Phase 1 1) 2008: 27 trials (Observational 4, Not applicable 13, Phase 4 5, Phase 2/3 3, Phase 2 2) 2009: 32 trials (Observational 3, Not applicable 14, Phase 4 4, Phase 3 2, Phase 2 8, Phase 1 1) 2010: 20 trials (Observational 1, Not applicable 10, Phase 4 5, Phase 2/3 1, Phase 2 2, Phase 1 1) 2011: 40 trials (Observational 5, Not applicable 21, Phase 4 3, Phase 3 3, Phase 2 6, Phase 1/2 1, Phase 1 1) 2012: 27 trials (Observational 4, Not applicable 16, Phase 4 3, Phase 3 1, Phase 2 1, Phase 1 2) 2013: 23 trials (Observational 2, Not applicable 14, Phase 4 2, Phase 3 1, Phase 2 2, Phase 1/2 1, Phase 1 1) 2014: 32 trials (Observational 5, Not applicable 22, Phase 3 1, Phase 2 1, Phase 1/2 2, Phase 1 1) 2015: 26 trials (Observational 4, Not applicable 17, Phase 2 3, Phase 1 2) 2016: 43 trials (Observational 7, Not applicable 27, Phase 4 5, Phase 2 2, Phase 1/2 1, Phase 1 1) 2017: 34 trials (Observational 5, Not applicable 27, Phase 4 1, Phase 1 1) 2018: 48 trials (Observational 2, Not applicable 38, Phase 4 3, Phase 3 3, Phase 2 1, Phase 1 1) 2019: 43 trials (Observational 7, Not applicable 32, Phase 2 3, Phase 1 1) 2020: 30 trials (Observational 4, Not applicable 19, Phase 4 2, Phase 2 2, Phase 1/2 1, Phase 1 2) 2021: 47 trials (Observational 4, Not applicable 31, Phase 4 2, Phase 3 1, Phase 2 6, Phase 1/2 1, Phase 1 2) 2022: 46 trials (Observational 4, Not applicable 40, Phase 4 1, Phase 1/2 1) 2023: 29 trials (Observational 3, Not applicable 20, Phase 4 2, Phase 2 4) 2024: 36 trials (Observational 4, Not applicable 30, Phase 4 1, Phase 1 1) 2025: 49 trials (Observational 10, Not applicable 35, Phase 4 1, Phase 2 2, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 39
2025 49
2024 36
2023 29
2022 46
2021 47
2020 30
2019 43
2018 48
2017 34

Forecast of the full-year count, planned starts included, not rows of this table: about 49 trials starting in 2026 and about 45 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 68 trials still running at the 2026-10-09 snapshot; registered median of 24 months across 529 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Glucose Intolerance trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 24
Phase 1/2 9
Phase 2 58
Phase 2/3 7
Phase 3 32
Phase 4 61
Not applicable 483
Observational 110

How many Glucose Intolerance trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 33
Recruiting 66
Enrolling by invitation 8
Active, not recruiting 30
Completed 489

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Glucose Intolerance trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Clinical Nutrition Research Center, Illinois Institute of Technology 8
Singapore Institute of Food and Biotechnology Innovation 8
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 5

Which drugs are being tested for Glucose Intolerance? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Exenatide 12
SITAGLIPTIN 8
BMS-512148 5
VALSARTAN 4
Voglibose 4

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
1% Metformin 24
Pioglitazone - TZD 12
Rosiglitazone XR 11
Oral Glucose Tolerance Test 8
Exercise 8

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Glucose Intolerance trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Hospitalizations 3,196 1
Hypoglycaemia 53 3
Angina unstable 31 4
Death 29 2
Myocardial infarction 24 3

Which publications cover Glucose Intolerance? (817)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages