Condition (MeSH)
Thyroid Hormone Resistance Syndrome
ClinicalTrials.gov lists 4 trials for Thyroid Hormone Resistance Syndrome or a narrower condition beneath it. Madrigal Pharmaceuticals, Inc. has the most among industry and government lead sponsors, with 2.
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Trials per phase
4 of the 4 trials are tagged with Thyroid Hormone Resistance Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Thyroid Hormone Resistance Syndrome trials start? (3)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 3
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2023 | 1 |
| 2021 | 2 |
| 2019 | 1 |
No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 4 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Thyroid Hormone Resistance Syndrome trials in? (2)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 3 | 2 |
| Observational | 2 |
How many Thyroid Hormone Resistance Syndrome trials are recruiting? (3)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 2 |
| Active, not recruiting | 1 |
| Completed | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Thyroid Hormone Resistance Syndrome trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Madrigal Pharmaceuticals, Inc. | 2 |
Which publications cover Thyroid Hormone Resistance Syndrome? (7)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Investigating the connection among thyroid function, sensitivity to thyroid hormones, and metabolic syndrome in euthyroid children and adolescents affected by type 1 diabetes. | Journal of pediatric endocrinology & metabolism : JPEM | 2024 | Yes |
| Impaired Sensitivity to Thyroid Hormones Is Associated With Diabetes and Metabolic Syndrome. | Diabetes care | 2019 | Yes |
| Fetal loss associated with excess thyroid hormone exposure. | JAMA | 2004 | Yes |
| Paternal imprinting of Galpha(s) in the human thyroid as the basis of TSH resistance in pseudohypoparathyroidism type 1a. | Biochemical and biophysical research communications | 2002 | Yes |
| Five new families with resistance to thyroid hormone not caused by mutations in the thyroid hormone receptor beta gene. | The Journal of clinical endocrinology and metabolism | 1999 | Yes |
Showing 5 of 7 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.