Condition (MeSH)
Persistent Vegetative State
ClinicalTrials.gov lists 86 trials for Persistent Vegetative State or a narrower condition beneath it.
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Trials per phase (log scale)
86 of the 86 trials are tagged with Persistent Vegetative State itself; the rest are tagged with a narrower condition beneath it.
When did Persistent Vegetative State trials start? (21)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 9
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 8 |
| 2025 | 4 |
| 2024 | 2 |
| 2023 | 4 |
| 2022 | 4 |
| 2021 | 4 |
| 2020 | 3 |
| 2019 | 5 |
| 2018 | 6 |
| 2017 | 9 |
Showing 10 of 21 earlier years.
No forecast is made for this condition: it averages 4.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 55 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Persistent Vegetative State trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 3 |
| Phase 1/2 | 2 |
| Phase 2 | 6 |
| Phase 2/3 | 2 |
| Phase 3 | 1 |
| Phase 4 | 2 |
| Not applicable | 39 |
| Observational | 31 |
How many Persistent Vegetative State trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 11 |
| Enrolling by invitation | 2 |
| Completed | 47 |
| Suspended | 2 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Persistent Vegetative State trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| AssisTech Sp. z o.o. | 1 |
| Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. | 1 |
Which drugs are being tested for Persistent Vegetative State? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| 18F-FDG | 1 |
| Sodium Valproate | 1 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| RPh201 | 2 |
| amantadine HCl ER | 2 |
| Sodium Chloride 9mg/mL | 1 |
| Zolpidem MR | 1 |
| Levetiracetam XR | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Persistent Vegetative State? (129)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| A Survey of Surrogates and Health Care Professionals Indicates Support of Cognitive Motor Dissociation-Assisted Prognostication. | Neurocritical care | 2025 | Yes |
| Predictors of Recovering Full Consciousness: Results From a Prospective Multisite Italian Study. | European journal of neurology | 2025 | Yes |
| Cognitive Motor Dissociation in Disorders of Consciousness. | The New England journal of medicine | 2024 | Yes |
| Behavioral signs of recovery from unresponsive wakefulness syndrome to emergence of minimally conscious state after severe brain injury. | Annals of physical and rehabilitation medicine | 2022 | Yes |
| Should Consistent Command-Following Be Added to the Criteria for Emergence From the Minimally Conscious State? | Archives of physical medicine and rehabilitation | 2022 | Yes |
Showing 5 of 129 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.