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Condition (MeSH)

Cystitis, Interstitial

ClinicalTrials.gov lists 231 trials for Cystitis, Interstitial or a narrower condition beneath it.

MeSH D018856 Urogenital Diseases C12 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 18 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 43 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 12 Phase 4 Phase 4 19 Not applicable Not applicable 65 Observational Observational 65 Phase 1 Phase 1 18 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 43 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 12 Phase 4 Phase 4 19 Not applicable Not applicable 65 Observational Observational 65

Trials per phase

231 of the 231 trials are tagged with Cystitis, Interstitial itself; the rest are tagged with a narrower condition beneath it.

Get the Cystitis, Interstitial report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Cystitis, Interstitial trials start? (25)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 16

1995: 1 trials (Phase 1/2 1) 2003: 3 trials (Observational 1, Phase 4 1, Phase 2 1) 2004: 7 trials (Observational 4, Not applicable 1, Phase 4 1, Phase 3 1) 2005: 3 trials (Not applicable 1, Phase 3 1, Phase 2 1) 2006: 10 trials (Observational 5, Not applicable 2, Phase 2 3) 2007: 9 trials (Observational 4, Not applicable 1, Phase 3 1, Phase 2 3) 2008: 7 trials (Observational 4, Not applicable 1, Phase 2 2) 2009: 13 trials (Observational 6, Not applicable 4, Phase 3 1, Phase 2 1, Phase 1 1) 2010: 14 trials (Observational 4, Not applicable 2, Phase 4 4, Phase 2 3, Phase 1 1) 2011: 9 trials (Observational 2, Not applicable 1, Phase 4 2, Phase 3 1, Phase 2 3) 2012: 14 trials (Observational 4, Not applicable 2, Phase 4 3, Phase 2 4, Phase 1 1) 2013: 9 trials (Observational 2, Not applicable 2, Phase 2 3, Phase 1/2 1, Phase 1 1) 2014: 7 trials (Not applicable 4, Phase 4 2, Phase 2 1) 2015: 15 trials (Observational 4, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2 5, Phase 1 1) 2016: 9 trials (Observational 5, Not applicable 2, Phase 3 2) 2017: 9 trials (Observational 1, Not applicable 2, Phase 4 2, Phase 2 2, Phase 1 2) 2018: 7 trials (Observational 3, Not applicable 4) 2019: 10 trials (Observational 3, Not applicable 4, Phase 3 1, Phase 2 1, Phase 1/2 1) 2020: 10 trials (Observational 1, Not applicable 2, Phase 2 5, Phase 1/2 1, Phase 1 1) 2021: 16 trials (Observational 2, Not applicable 7, Phase 4 2, Phase 3 1, Phase 2 1, Phase 1/2 1, Phase 1 2) 2022: 13 trials (Observational 2, Not applicable 7, Phase 3 1, Phase 2 1, Phase 1 2) 2023: 10 trials (Observational 3, Not applicable 2, Phase 3 1, Phase 2/3 2, Phase 2 2) 2024: 14 trials (Observational 5, Not applicable 5, Phase 4 1, Phase 2/3 2, Phase 2 1) 2025: 5 trials (Not applicable 3, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 7
2025 5
2024 14
2023 10
2022 13
2021 16
2020 10
2019 10
2018 7
2017 9

Showing 10 of 25 earlier years.

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Forecast of the full-year count, planned starts included, not rows of this table: about 7 trials starting in 2026 and about 7 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 7 already registered with a 2026 start date: at the cutoff, 2 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.

Prediction, not a registry value: median of 36 months from start to primary completion across 12 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 155 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Cystitis, Interstitial trials in? (8)

Shown in this order: phase order.

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Trials by phase
Phase Trials
Phase 1 18
Phase 1/2 5
Phase 2 43
Phase 2/3 4
Phase 3 12
Phase 4 19
Not applicable 65
Observational 65

How many Cystitis, Interstitial trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 6
Recruiting 24
Enrolling by invitation 1
Active, not recruiting 3
Completed 129

Showing 5 of 8 statuses.

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Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Cystitis, Interstitial trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Allergan 7
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 7
Walter Reed National Military Medical Center 5
Assaf-Harofeh Medical Center 4

Which drugs are being tested for Cystitis, Interstitial? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Dimethyl Sulfoxide 4

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
type A botulinum toxin 5
L:Lidocaine 4
Acupuncture 3
Hyperbaric Oxygen 3
LiRIS® 2

Showing 5 of 14 interventions.

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These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Cystitis, Interstitial trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Anaemia 8 1
Acute Kidney Injury 5 1
Urinary Tract Infection 4 2
Urosepsis 4 3
Acute Respiratory Failure 2 1

Showing 5 of 10 adverse events.

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Which publications cover Cystitis, Interstitial? (238)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Algorithm-Based Mobile Texting Platform for the Self-Management of Interstitial Cystitis/Bladder Pain Syndrome: Pilot Study Evaluating Feasibility, Usability, and Potential Utility. Urology practice 2025 Yes
Relationship of Sex and Diagnosis With Symptoms and Illness Impact in Urologic Chronic Pelvic Pain; A Mapp Network Analysis. Neurourology and urodynamics 2025 Yes
Augmentation of Interstitial Cystitis-Bladder Pain Syndrome Treatment With Meditation and Yoga: A Randomized Controlled Trial. Obstetrics and gynecology 2025 Yes
A single-center, phase 1/2a trial of hESC-derived mesenchymal stem cells (MR-MC-01) for safety and efficacy in interstitial cystitis patients. Stem cells translational medicine 2025 Yes
Carry-over effects in GAG therapy efficacy trial solution for bladder pain syndrome/interstitial cystitis (GETSBI study): an interim analysis. BMJ open 2025 Yes

Showing 5 of 238 publications.

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Prevalence (12)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Interstitial cystitis Point prevalence 1-5 / 10 000 United States US Exact
Interstitial cystitis Point prevalence 1-5 / 10 000 United States US Unspecified
Interstitial cystitis Point prevalence 1-5 / 10 000 United States US Exact
Interstitial cystitis Point prevalence 1-5 / 10 000 Finland Not stated Unspecified
Interstitial cystitis Annual incidence 1-9 / 1 000 000 Finland Not stated Exact

Showing 5 of 12 prevalence observations.

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Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Interstitial cystitis 37202 Exact Orphadata Science knowledge files, Product 1
Interstitial cystitis 37202 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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