Condition (MeSH)
Intracranial Hypotension
ClinicalTrials.gov lists 20 trials for Intracranial Hypotension or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
20 of the 20 trials are tagged with Intracranial Hypotension itself; the rest are tagged with a narrower condition beneath it.
When did Intracranial Hypotension trials start? (11)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 3 |
| 2024 | 3 |
| 2023 | 2 |
| 2022 | 1 |
| 2021 | 1 |
| 2020 | 2 |
| 2017 | 3 |
| 2015 | 1 |
| 2014 | 1 |
Showing 10 of 11 earlier years.
No forecast is made for this condition: it averages 2.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Intracranial Hypotension trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Not applicable | 7 |
| Observational | 11 |
How many Intracranial Hypotension trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 4 |
| Enrolling by invitation | 1 |
| Completed | 9 |
| Suspended | 1 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which drugs are being tested for Intracranial Hypotension? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Whole Blood | 1 |
Interventions as named in the registry (4)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Lumbar puncture | 1 |
| TISSEEL | 1 |
| Atorvastatin plus Dexamethasone | 1 |
| injection of HES " Voluven® " | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Intracranial Hypotension? (40)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Incidence of spontaneous intracranial hypotension in Olmsted County, Minnesota: 2019-2021. | Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences | 2025 | Yes |
| No evidence of intracranial hypotension in persistent post-traumatic headache: A magnetic resonance imaging study. | Cephalalgia : an international journal of headache | 2025 | Yes |
| Distinct Pattern of Membrane Formation With Spinal Cerebrospinal Fluid Leaks in Spontaneous Intracranial Hypotension. | Operative neurosurgery (Hagerstown, Md.) | 2024 | Yes |
| Infratentorial Superficial Siderosis and Spontaneous Intracranial Hypotension. | Annals of neurology | 2023 | Yes |
| Epidural Blood Patching in Spontaneous Intracranial Hypotension-Do we Really Seal the Leak? | Clinical neuroradiology | 2023 | Yes |
Showing 5 of 40 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.