Condition (MeSH)
Carbamoyl-Phosphate Synthase I Deficiency Disease
ClinicalTrials.gov lists 9 trials for Carbamoyl-Phosphate Synthase I Deficiency Disease or a narrower condition beneath it.
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Trials per phase
9 of the 9 trials are tagged with Carbamoyl-Phosphate Synthase I Deficiency Disease itself; the rest are tagged with a narrower condition beneath it.
When did Carbamoyl-Phosphate Synthase I Deficiency Disease trials start? (7)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2022 | 3 |
| 2020 | 1 |
| 2018 | 1 |
| 2012 | 1 |
| 2011 | 1 |
| 2010 | 1 |
| 2007 | 1 |
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 9 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Carbamoyl-Phosphate Synthase I Deficiency Disease trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Observational | 5 |
How many Carbamoyl-Phosphate Synthase I Deficiency Disease trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 2 |
| Active, not recruiting | 1 |
| Completed | 3 |
| Terminated | 1 |
| Withdrawn | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which serious adverse events do Carbamoyl-Phosphate Synthase I Deficiency Disease trials report? (6)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Gastrointestinal Disorders | 9 | 1 |
| Infections and Infestations | 6 | 1 |
| Nervous System | 3 | 1 |
| Injury | 2 | 1 |
| Metabolic and Nutritional | 2 | 1 |
Showing 5 of 6 adverse events.
Which publications cover Carbamoyl-Phosphate Synthase I Deficiency Disease? (1)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Survival after treatment with phenylacetate and benzoate for urea-cycle disorders. | The New England journal of medicine | 2007 | No |
Prevalence (15)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Carbamoyl-phosphate synthetase 1 deficiency | Prevalence at birth | <1 / 1 000 000 | United States | US | Exact |
| Carbamoyl-phosphate synthetase 1 deficiency | Prevalence at birth | <1 / 1 000 000 | United States | US | Exact |
| Carbamoyl-phosphate synthetase 1 deficiency | Prevalence at birth | <1 / 1 000 000 | United States | US | Unspecified |
| Carbamoyl-phosphate synthetase 1 deficiency | Prevalence at birth | 1-9 / 1 000 000 | Finland | Not stated | Unspecified |
| Carbamoyl-phosphate synthetase 1 deficiency | Prevalence at birth | 1-9 / 1 000 000 | Finland | Not stated | Exact |
Showing 5 of 15 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Carbamoyl-phosphate synthetase 1 deficiency | 147 | Exact | Orphadata Science knowledge files, Product 1 |
| Carbamoyl-phosphate synthetase 1 deficiency | 147 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.