Condition (MeSH)
Brain Injury, Chronic
ClinicalTrials.gov lists 45 trials for Brain Injury, Chronic or a narrower condition beneath it. MD Stem Cells has the most among industry and government lead sponsors, with 2.
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Trials per phase
19 of the 45 trials are tagged with Brain Injury, Chronic itself; the rest are tagged with a narrower condition beneath it.
When did Brain Injury, Chronic trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 10
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 4 |
| 2024 | 2 |
| 2023 | 2 |
| 2022 | 1 |
| 2021 | 10 |
| 2019 | 1 |
| 2018 | 3 |
| 2017 | 2 |
| 2016 | 6 |
Showing 10 of 16 earlier years.
No forecast is made for this condition: it averages 2.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 24 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Brain Injury, Chronic trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Not applicable | 16 |
| Observational | 19 |
How many Brain Injury, Chronic trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 9 |
| Enrolling by invitation | 1 |
| Completed | 21 |
| Terminated | 1 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Brain Injury, Chronic trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| MD Stem Cells | 2 |
| Avid Radiopharmaceuticals | 1 |
| Centre for Neuro Skills | 1 |
| CereMark Pharma, LLC | 1 |
| East Kent Hospitals University NHS Foundation Trust | 1 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Hyperbaric Oxygen | 1 |
| Amyvid PET Scan | 1 |
| cerebrospinal fluid | 1 |
| Intranasal auto-M2-BFs | 1 |
| MUSE Stem Cell Therapy | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Brain Injury, Chronic? (71)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Comparative Efficacy of High-Intensity Training Versus Conventional Training in Individuals With Chronic Traumatic Brain Injury: A Pilot Randomized Controlled Study. | Journal of neurotrauma | 2024 | Yes |
| Gait Performance in People with Symptomatic, Chronic Mild Traumatic Brain Injury. | Journal of neurotrauma | 2021 | Yes |
| High-Definition Transcranial Direct Current Stimulation to Improve Verbal Retrieval Deficits in Chronic Traumatic Brain Injury. | Journal of neurotrauma | 2020 | Yes |
| Relationship of Cerebral Blood Flow to Cognitive Function and Recovery in Early Chronic Traumatic Brain Injury. | Journal of neurotrauma | 2020 | Yes |
| Impaired cerebral blood flow regulation in chronic traumatic brain injury. | Brain research | 2020 | Yes |
Showing 5 of 71 publications.
Prevalence (1)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Dementia pugilistica | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Unspecified |
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and rare-disease identity.