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Condition (MeSH)

Autonomic Dysreflexia

ClinicalTrials.gov lists 30 trials for Autonomic Dysreflexia or a narrower condition beneath it. James J. Peters Veterans Affairs Medical Center has the most among industry and government lead sponsors, with 6.

MeSH D020211 Nervous System Diseases C10
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Phase 1 Phase 1 1 Phase 2 Phase 2 3 Phase 2/3 Phase 2/3 1 Phase 4 Phase 4 3 Not applicable Not applicable 16 Observational Observational 6 Phase 1 Phase 1 1 Phase 2 Phase 2 3 Phase 2/3 Phase 2/3 1 Phase 4 Phase 4 3 Not applicable Not applicable 16 Observational Observational 6

Trials per phase

30 of the 30 trials are tagged with Autonomic Dysreflexia itself; the rest are tagged with a narrower condition beneath it.

Get the Autonomic Dysreflexia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Autonomic Dysreflexia trials start? (13)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 4

2004: 1 trials (Not applicable 1) 2012: 2 trials (Observational 1, Phase 4 1) 2013: 4 trials (Observational 2, Not applicable 1, Phase 4 1) 2016: 4 trials (Observational 1, Not applicable 1, Phase 2 2) 2017: 1 trials (Phase 2/3 1) 2019: 1 trials (Phase 4 1) 2020: 2 trials (Not applicable 2) 2021: 2 trials (Not applicable 2) 2022: 3 trials (Not applicable 3) 2023: 2 trials (Not applicable 2) 2024: 2 trials (Not applicable 1, Phase 1 1) 2025: 3 trials (Observational 1, Not applicable 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 3
2025 3
2024 2
2023 2
2022 3
2021 2
2020 2
2019 1
2017 1
2016 4

No forecast is made for this condition: it averages 2.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 52 months across 16 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Autonomic Dysreflexia trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 2 3
Phase 2/3 1
Phase 4 3
Not applicable 16
Observational 6

How many Autonomic Dysreflexia trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 6
Enrolling by invitation 1
Completed 16
Unknown status 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Autonomic Dysreflexia trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
James J. Peters Veterans Affairs Medical Center 6
Swiss Paraplegic Research, Nottwil 1

Which drugs are being tested for Autonomic Dysreflexia? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Pyridostigmine 1

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Midodrine 2.5 mg tab 2
Mecamylamine Oral Tablet 1
Bladder chemodenervation (Botox) 1
Lidocaine Lubricant 1
Fesoterodine ER (fasted) 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Autonomic Dysreflexia? (55)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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