Condition (MeSH)
Vagus Nerve Diseases
ClinicalTrials.gov lists 62 trials for Vagus Nerve Diseases or a narrower condition beneath it. APrevent Biotech GmbH has the most among industry and government lead sponsors, with 2.
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Trials per phase (log scale)
4 of the 62 trials are tagged with Vagus Nerve Diseases itself; the rest are tagged with a narrower condition beneath it.
When did Vagus Nerve Diseases trials start? (23)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 8
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 4 |
| 2024 | 4 |
| 2023 | 4 |
| 2022 | 3 |
| 2021 | 2 |
| 2020 | 5 |
| 2019 | 8 |
| 2018 | 5 |
| 2016 | 3 |
Showing 10 of 23 earlier years.
No forecast is made for this condition: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 30 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Vagus Nerve Diseases trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Phase 2 | 4 |
| Phase 3 | 3 |
| Phase 4 | 1 |
| Not applicable | 36 |
| Observational | 16 |
How many Vagus Nerve Diseases trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 5 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 1 |
| Completed | 31 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Vagus Nerve Diseases trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| APrevent Biotech GmbH | 2 |
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Corticoids | 1 |
| centrifuged autologous fat | 1 |
| Renuva Allograft Adipose Matrix | 1 |
| Sugamadex | 1 |
| Dexamethasone/Dexamethasone acetate | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Vagus Nerve Diseases? (7)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Vagal dysfunction and small intestinal bacterial overgrowth: novel pathways to chronic inflammation in HIV. | AIDS (London, England) | 2018 | Yes |
| Chronic fatigue syndrome from vagus nerve infection: a psychoneuroimmunological hypothesis. | Medical hypotheses | 2013 | Yes |
| The relationship between heart rate variability and time-course of carcinoembryonic antigen in colorectal cancer. | Autonomic neuroscience : basic & clinical | 2012 | Yes |
| Selective vagal denervation of the sinus and atrioventricular nodes, guided by vagal reflexes induced by high frequency stimulation, to treat refractory neurally mediated syncope. | Journal of cardiovascular electrophysiology | 2009 | Yes |
| Vagal dysfunction in irritable bowel syndrome assessed by rectal distension and baroreceptor sensitivity. | Neurogastroenterology and motility | 2008 | Yes |
Showing 5 of 7 publications.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, and rare-disease identity.