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Condition (MeSH)

Neuralgia, Postherpetic

ClinicalTrials.gov lists 195 trials for Neuralgia, Postherpetic or a narrower condition beneath it. Pfizer's Upjohn has merged with Mylan to form Viatris Inc. has the most among industry and government lead sponsors, with 8.

MeSH D051474 Nervous System Diseases C10 C23
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Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 63 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 24 Phase 4 Phase 4 19 Not applicable Not applicable 44 Observational Observational 28 Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 63 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 24 Phase 4 Phase 4 19 Not applicable Not applicable 44 Observational Observational 28

Trials per phase (log scale)

195 of the 195 trials are tagged with Neuralgia, Postherpetic itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Neuralgia, Postherpetic trials start? (28)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 16

1993: 1 trials (Phase 2 1) 1998: 2 trials (Phase 3 2) 2001: 1 trials (Observational 1) 2002: 5 trials (Not applicable 1, Phase 4 1, Phase 2 3) 2003: 4 trials (Phase 4 1, Phase 3 2, Phase 2 1) 2004: 7 trials (Not applicable 1, Phase 4 3, Phase 2 3) 2005: 4 trials (Phase 3 1, Phase 2/3 1, Phase 2 2) 2006: 9 trials (Phase 3 5, Phase 2/3 1, Phase 2 2, Phase 1 1) 2007: 9 trials (Phase 4 1, Phase 3 1, Phase 2 6, Phase 1 1) 2008: 11 trials (Phase 4 1, Phase 3 2, Phase 2 8) 2009: 9 trials (Observational 1, Phase 2 6, Phase 1/2 2) 2010: 11 trials (Phase 4 3, Phase 3 3, Phase 2 5) 2011: 11 trials (Observational 2, Not applicable 2, Phase 4 3, Phase 3 1, Phase 2 3) 2012: 8 trials (Observational 2, Phase 4 2, Phase 2 4) 2013: 5 trials (Observational 1, Not applicable 1, Phase 2 3) 2014: 3 trials (Phase 4 1, Phase 2 2) 2015: 10 trials (Observational 1, Not applicable 1, Phase 3 3, Phase 2 3, Phase 1/2 1, Phase 1 1) 2016: 6 trials (Observational 1, Not applicable 2, Phase 2 1, Phase 1 2) 2017: 7 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 1, Phase 1 2) 2018: 5 trials (Observational 3, Not applicable 2) 2019: 7 trials (Observational 1, Not applicable 4, Phase 4 1, Phase 2 1) 2020: 8 trials (Observational 1, Not applicable 4, Phase 4 1, Phase 2 1, Phase 1 1) 2021: 5 trials (Observational 1, Not applicable 3, Phase 3 1) 2022: 8 trials (Observational 2, Not applicable 2, Phase 2 2, Phase 1 2) 2023: 7 trials (Observational 4, Not applicable 1, Phase 3 1, Phase 2 1) 2024: 6 trials (Observational 1, Not applicable 4, Phase 4 1) 2025: 16 trials (Observational 3, Not applicable 12, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 8
2025 16
2024 6
2023 7
2022 8
2021 5
2020 8
2019 7
2018 5
2017 7

Forecast of the full-year count, planned starts included, not rows of this table: about 10 trials starting in 2026 and about 12 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 30 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 133 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Neuralgia, Postherpetic trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 12
Phase 1/2 3
Phase 2 63
Phase 2/3 2
Phase 3 24
Phase 4 19
Not applicable 44
Observational 28

How many Neuralgia, Postherpetic trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 8
Recruiting 16
Active, not recruiting 3
Completed 128
Terminated 16

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Neuralgia, Postherpetic trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 8
Pfizer 7
Merck Sharp & Dohme LLC 5
NeurogesX 5
UCB Pharma 4

Which drugs are being tested for Neuralgia, Postherpetic? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Pregabalin 20

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Capsaicin 8% 6
Gabapentin 6% 6
Valacyclovir arrow 4
type A botulinum toxin 4
L:Lidocaine 4

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Neuralgia, Postherpetic trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 13 10
Angina pectoris 7 7
Coronary artery disease 6 6
Dizziness 6 5
Myocardial infarction 6 6

Which publications cover Neuralgia, Postherpetic? (140)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Low-Dose Valacyclovir for Postherpetic Neuralgia in the Zoster Eye Disease Study: A Randomized Clinical Trial. JAMA ophthalmology 2025 Yes
Observation on the effect of platelet-rich plasma combined with drugs in the treatment of herpes zoster neuralgia. The International journal of neuroscience 2024 Yes
PROCESS Trial: Effect of Duloxetine Premedication for Postherpetic Neuralgia Within 72 Hours of Herpes Zoster Reactivation-A Randomized Controlled Trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Yes
Immune response to the recombinant herpes zoster vaccine in people living with HIV over 50 years of age compared to non-HIV age-/gender-matched controls (SHINGR'HIV): a multicenter, international, non-randomized clinical trial study protocol. BMC infectious diseases 2024 Yes
A bibliometric analysis and visualization of acupuncture and moxibustion therapy for herpes zoster and postherpetic neuralgia. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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