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Condition (MeSH)

Urinary Bladder, Overactive

ClinicalTrials.gov lists 801 trials for Urinary Bladder, Overactive or a narrower condition beneath it. Astellas Pharma Inc has the most among industry and government lead sponsors, with 42.

MeSH D053201 Urogenital Diseases C12 C23
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Phase 1 Phase 1 58 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 67 Phase 2/3 Phase 2/3 6 Phase 3 Phase 3 89 Phase 4 Phase 4 134 Not applicable Not applicable 272 Observational Observational 167 Phase 1 Phase 1 58 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 67 Phase 2/3 Phase 2/3 6 Phase 3 Phase 3 89 Phase 4 Phase 4 134 Not applicable Not applicable 272 Observational Observational 167

Trials per phase (log scale)

801 of the 801 trials are tagged with Urinary Bladder, Overactive itself; the rest are tagged with a narrower condition beneath it.

Get the Urinary Bladder, Overactive report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Urinary Bladder, Overactive trials start? (26)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 45

2001: 1 trials (Phase 2 1) 2002: 3 trials (Observational 1, Phase 3 2) 2003: 7 trials (Not applicable 1, Phase 3 4, Phase 2 2) 2004: 15 trials (Not applicable 1, Phase 4 2, Phase 3 8, Phase 2/3 1, Phase 2 3) 2005: 12 trials (Observational 2, Not applicable 1, Phase 4 3, Phase 3 1, Phase 2 5) 2006: 28 trials (Observational 5, Not applicable 1, Phase 4 9, Phase 3 6, Phase 2 5, Phase 1/2 1, Phase 1 1) 2007: 34 trials (Observational 4, Not applicable 1, Phase 4 7, Phase 3 7, Phase 2/3 1, Phase 2 8, Phase 1 6) 2008: 35 trials (Observational 4, Not applicable 7, Phase 4 8, Phase 3 9, Phase 2 3, Phase 1 4) 2009: 45 trials (Observational 12, Not applicable 7, Phase 4 14, Phase 3 7, Phase 2 2, Phase 1 3) 2010: 34 trials (Observational 8, Not applicable 4, Phase 4 9, Phase 3 4, Phase 2/3 2, Phase 2 5, Phase 1 2) 2011: 22 trials (Observational 7, Not applicable 3, Phase 4 6, Phase 2 3, Phase 1 3) 2012: 37 trials (Observational 11, Not applicable 7, Phase 4 6, Phase 3 4, Phase 2 3, Phase 1 6) 2013: 30 trials (Observational 5, Not applicable 8, Phase 4 6, Phase 3 6, Phase 2 3, Phase 1 2) 2014: 38 trials (Observational 6, Not applicable 18, Phase 4 4, Phase 3 3, Phase 2/3 1, Phase 2 1, Phase 1/2 1, Phase 1 4) 2015: 35 trials (Observational 11, Not applicable 8, Phase 4 7, Phase 3 3, Phase 2 1, Phase 1/2 1, Phase 1 4) 2016: 39 trials (Observational 5, Not applicable 12, Phase 4 6, Phase 3 8, Phase 2 3, Phase 1/2 1, Phase 1 4) 2017: 36 trials (Observational 17, Not applicable 10, Phase 4 3, Phase 2 2, Phase 1/2 1, Phase 1 3) 2018: 35 trials (Observational 7, Not applicable 14, Phase 4 6, Phase 3 3, Phase 2 4, Phase 1 1) 2019: 34 trials (Observational 7, Not applicable 18, Phase 4 4, Phase 3 3, Phase 2 1, Phase 1 1) 2020: 35 trials (Observational 7, Not applicable 16, Phase 4 2, Phase 3 1, Phase 2 2, Phase 1 7) 2021: 40 trials (Observational 12, Not applicable 17, Phase 4 7, Phase 3 1, Phase 1 3) 2022: 36 trials (Observational 7, Not applicable 17, Phase 4 9, Phase 3 2, Phase 1/2 1) 2023: 39 trials (Observational 4, Not applicable 26, Phase 4 2, Phase 2/3 1, Phase 2 2, Phase 1/2 1, Phase 1 3) 2024: 34 trials (Observational 9, Not applicable 19, Phase 4 3, Phase 3 1, Phase 2 2) 2025: 43 trials (Observational 6, Not applicable 31, Phase 4 5, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 46
2025 43
2024 34
2023 39
2022 36
2021 40
2020 35
2019 34
2018 35
2017 36

Forecast of the full-year count, planned starts included, not rows of this table: about 56 trials starting in 2026 and about 45 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 34 months from start to primary completion across 54 trials still running at the 2026-10-09 snapshot; registered median of 18 months across 549 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Urinary Bladder, Overactive trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 58
Phase 1/2 8
Phase 2 67
Phase 2/3 6
Phase 3 89
Phase 4 134
Not applicable 272
Observational 167

How many Urinary Bladder, Overactive trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 35
Recruiting 63
Enrolling by invitation 7
Active, not recruiting 11
Completed 491

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Urinary Bladder, Overactive trials? (9)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Astellas Pharma Inc 42
Pfizer 29
Allergan 24
Bayer 11
Astellas Pharma Europe B.V. 9

Which drugs are being tested for Urinary Bladder, Overactive? (8)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Tolterodine 47
Darifenacin 15
Vibegron 9
Tamsulosin 8
Trospium 8

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Solifenacin PO 76
mirabegron OCAS 71
type A botulinum toxin 41
Fesoterodine ER (fasted) 36
3% oxybutynin 14

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Urinary Bladder, Overactive trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 68 28
Osteoarthritis 66 19
Urinary tract infection 47 19
Atrial fibrillation 39 24
Breast cancer 32 20

Which publications cover Urinary Bladder, Overactive? (699)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages