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Condition (MeSH)

Lissencephaly

ClinicalTrials.gov lists 6 trials for Lissencephaly or a narrower condition beneath it.

MeSH D054082 Nervous System Diseases C10 C16 Listed by Orphanet as a rare disease
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Not applicable Not applicable 1 Observational Observational 5 Not applicable Not applicable 1 Observational Observational 5

Trials per phase

2 of the 6 trials are tagged with Lissencephaly itself; the rest are tagged with a narrower condition beneath it.

Get the Lissencephaly report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Lissencephaly trials start? (6)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Not applicable
  • Observational

Top of scale: 1

1996: 1 trials (Observational 1) 2006: 1 trials (Observational 1) 2009: 1 trials (Observational 1) 2013: 1 trials (Observational 1) 2022: 1 trials (Not applicable 1) 2023: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2023 1
2022 1
2013 1
2009 1
2006 1
1996 1

No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 6 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Lissencephaly trials in? (2)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Not applicable 1
Observational 5

How many Lissencephaly trials are recruiting? (2)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 4
Unknown status 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which publications cover Lissencephaly? (2)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Novel PCNT variants in MOPDII with attenuated growth restriction and pachygyria. Clinical genetics 2020 Yes
Analysis of 17 genes detects mutations in 81% of 811 patients with lissencephaly. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Yes

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Lissencephaly 48471 Exact Orphadata Science knowledge files, Product 1
Lissencephaly 48471 Exact Orphanet Rare Disease Ontology (ORDO)

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, and prevalence.

Not computed for conditions with fewer than 10 trials: drugs tested.

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