Skip to content
Pharma Observatory a Scientist.com platform

Condition (MeSH)

No-Reflow Phenomenon

ClinicalTrials.gov lists 26 trials for No-Reflow Phenomenon or a narrower condition beneath it.

MeSH D054318 Pathological Conditions, Signs and Symptoms C23
Email me this page as a PDF

Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 3 Phase 3 1 Phase 4 Phase 4 8 Not applicable Not applicable 7 Observational Observational 8 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 3 Phase 3 1 Phase 4 Phase 4 8 Not applicable Not applicable 7 Observational Observational 8

Trials per phase

26 of the 26 trials are tagged with No-Reflow Phenomenon itself; the rest are tagged with a narrower condition beneath it.

Get the No-Reflow Phenomenon report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did No-Reflow Phenomenon trials start? (14)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 4

2004: 1 trials (Observational 1) 2006: 1 trials (Phase 4 1) 2011: 1 trials (Phase 4 1) 2014: 1 trials (Phase 4 1) 2015: 2 trials (Observational 1, Phase 4 1) 2016: 2 trials (Not applicable 2) 2017: 1 trials (Observational 1) 2018: 1 trials (Not applicable 1) 2020: 2 trials (Observational 1, Not applicable 1) 2021: 2 trials (Not applicable 1, Phase 4 1) 2022: 3 trials (Observational 1, Not applicable 1, Phase 4 1) 2024: 4 trials (Not applicable 1, Phase 3 1, Phase 2 1, Phase 1/2 1) 2025: 4 trials (Observational 2, Phase 4 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 4
2024 4
2022 3
2021 2
2020 2
2018 1
2017 1
2016 2
2015 2

No forecast is made for this condition: it averages 2.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are No-Reflow Phenomenon trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 1
Phase 2 1
Phase 3 1
Phase 4 8
Not applicable 7
Observational 8

How many No-Reflow Phenomenon trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 4
Active, not recruiting 1
Completed 10
Unknown status 7

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most No-Reflow Phenomenon trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Hull University Teaching Hospitals NHS Trust 1
Sheba Medical Center 1

Which drugs are being tested for No-Reflow Phenomenon? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Nicorandil 2
TIROFIBAN 2

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Epinephrin 3
SR verapamil 2
Empagliflozine 2
Adenosine pre-medication 1
Ticagrelor (Brilique) 90 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover No-Reflow Phenomenon? (65)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages