Condition (MeSH)
Primary Graft Dysfunction
ClinicalTrials.gov lists 25 trials for Primary Graft Dysfunction or a narrower condition beneath it.
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Trials per phase
25 of the 25 trials are tagged with Primary Graft Dysfunction itself; the rest are tagged with a narrower condition beneath it.
When did Primary Graft Dysfunction trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 1 |
| 2023 | 3 |
| 2022 | 1 |
| 2021 | 1 |
| 2020 | 1 |
| 2019 | 1 |
| 2018 | 2 |
| 2017 | 3 |
| 2015 | 2 |
Showing 10 of 16 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Primary Graft Dysfunction trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 4 |
| Phase 2/3 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
| Not applicable | 4 |
| Observational | 13 |
How many Primary Graft Dysfunction trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 4 |
| Active, not recruiting | 2 |
| Completed | 8 |
| Terminated | 4 |
| Withdrawn | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which drugs are being tested for Primary Graft Dysfunction? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Maraviroc | 1 |
| Vitamin C | 1 |
| Treprostinil | 1 |
| Fresh Frozen Plasma | 1 |
Interventions as named in the registry (4)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Surfactant | 1 |
| Thymoglobulin [Anti-Thymocyte Globulin (Rabbit)] | 1 |
| Nitrite | 1 |
| N-Acetylcystein | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Primary Graft Dysfunction trials report? (1)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Respiratory failure | 1 | 1 |
Which publications cover Primary Graft Dysfunction? (88)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Prognosis and Risks for Probable Chronic Lung Allograft Dysfunction: A Prospective Multicenter Study. | American journal of respiratory and critical care medicine | 2025 | Yes |
| Validation of a Pretransplant Risk Prediction Model for Early Allograft Dysfunction After Living-donor Liver Transplantation. | Transplantation | 2025 | Yes |
| Extracellular vesicles in lung donor plasma: Potential indicators of donor organ quality. | The Journal of thoracic and cardiovascular surgery | 2025 | Yes |
| Persistent and progressive acute lung allograft dysfunction is linked to cell compositional and transcriptional changes in small airways. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 2025 | Yes |
| The Impact of Donor Smoking on Primary Graft Dysfunction and Mortality after Lung Transplantation. | American journal of respiratory and critical care medicine | 2024 | Yes |
Showing 5 of 88 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.