Condition (MeSH)
Vulvodynia
ClinicalTrials.gov lists 106 trials for Vulvodynia or a narrower condition beneath it. Western Galilee Hospital-Nahariya has the most among industry and government lead sponsors, with 7.
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Trials per phase (log scale)
106 of the 106 trials are tagged with Vulvodynia itself; the rest are tagged with a narrower condition beneath it.
When did Vulvodynia trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 10
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 8 |
| 2024 | 5 |
| 2023 | 4 |
| 2022 | 10 |
| 2021 | 3 |
| 2020 | 1 |
| 2019 | 6 |
| 2018 | 9 |
| 2017 | 1 |
Showing 10 of 24 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 7 trials starting in 2026 and about 7 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 14 trials still running at the 2026-10-09 snapshot; registered median of 27 months across 70 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Vulvodynia trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 12 |
| Phase 2/3 | 2 |
| Phase 3 | 10 |
| Phase 4 | 2 |
| Not applicable | 55 |
| Observational | 24 |
How many Vulvodynia trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 5 |
| Recruiting | 12 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 4 |
| Completed | 60 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Vulvodynia trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Western Galilee Hospital-Nahariya | 7 |
| Ipsen | 2 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Acupuncture | 4 |
| type A botulinum toxin | 4 |
| L:Lidocaine | 4 |
| Gabapentin 6% | 2 |
| Treatment As Usual | 2 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Vulvodynia trials report? (5)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Seizure | 1 | 1 |
| Severe Acute Pancreatitis | 1 | 1 |
| asthma with acute exacerbation | 1 | 1 |
| cluster headache | 1 | 1 |
| unstable angina and malignant hypertension | 1 | 1 |
Which publications cover Vulvodynia? (88)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Inflammation-induced mast cell-derived nerve growth factor: a key player in chronic vulvar pain? | Brain : a journal of neurology | 2025 | Yes |
| Photobiomodulation therapy for the treatment of vulvar pain among those with provoked vestibulodynia: a randomized controlled trial. | The journal of sexual medicine | 2025 | Yes |
| Phase 2 randomized study of abobotulinumtoxinA in patients with provoked vestibulodynia: dose-finding results. | The journal of sexual medicine | 2025 | Yes |
| Pelvic floor examination in vulvodynia: VAMP protocol validation in correlation with central sensitization. | Women's health (London, England) | 2025 | Yes |
| Immunohistochemical staining with CD117 and PGP9.5 of excised vestibular tissue from patients with neuroproliferative vestibulodynia. | The journal of sexual medicine | 2024 | Yes |
Showing 5 of 88 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.