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Condition (MeSH)

Low Tension Glaucoma

ClinicalTrials.gov lists 65 trials for Low Tension Glaucoma or a narrower condition beneath it. Qlaris Bio, Inc. has the most among industry and government lead sponsors, with 3.

MeSH D057066 Eye Diseases C11
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Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 6 Phase 4 Phase 4 8 Not applicable Not applicable 17 Observational Observational 33 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 6 Phase 4 Phase 4 8 Not applicable Not applicable 17 Observational Observational 33

Trials per phase (log scale)

65 of the 65 trials are tagged with Low Tension Glaucoma itself; the rest are tagged with a narrower condition beneath it.

Get the Low Tension Glaucoma report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Low Tension Glaucoma trials start? (23)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 7

1998: 1 trials (Phase 2 1) 2004: 1 trials (Observational 1) 2005: 1 trials (Observational 1) 2006: 4 trials (Observational 3, Not applicable 1) 2007: 1 trials (Observational 1) 2008: 4 trials (Observational 4) 2009: 1 trials (Observational 1) 2010: 4 trials (Observational 2, Not applicable 1, Phase 4 1) 2011: 5 trials (Observational 4, Not applicable 1) 2012: 1 trials (Not applicable 1) 2013: 6 trials (Observational 4, Not applicable 1, Phase 4 1) 2014: 1 trials (Not applicable 1) 2015: 1 trials (Phase 2 1) 2016: 3 trials (Observational 2, Phase 4 1) 2017: 7 trials (Observational 2, Not applicable 2, Phase 4 2, Phase 2 1) 2018: 2 trials (Not applicable 2) 2019: 1 trials (Observational 1) 2020: 2 trials (Observational 1, Not applicable 1) 2021: 4 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 2 1) 2022: 3 trials (Not applicable 2, Phase 4 1) 2024: 4 trials (Observational 2, Not applicable 1, Phase 4 1) 2025: 5 trials (Observational 3, Not applicable 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 3
2025 5
2024 4
2022 3
2021 4
2020 2
2019 1
2018 2
2017 7
2016 3

No forecast is made for this condition: it averages 3.2 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 30 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 42 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Low Tension Glaucoma trials in? (5)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 1
Phase 2 6
Phase 4 8
Not applicable 17
Observational 33

How many Low Tension Glaucoma trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 5
Active, not recruiting 2
Completed 38
Terminated 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Low Tension Glaucoma trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Qlaris Bio, Inc. 3
Alcon Research 1
Allergan 1
BelkinVision 1

Which drugs are being tested for Low Tension Glaucoma? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Timolol hemihydrate 2
Brimonidine 2

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Timolol Maleate PF 0.5% Ophthalmic Solution (Timolol) 2
QLS-111 Ophthalmic Solution (0.015%) 2
travoprost 0.003% 1
Bimatoprost Ophthalmic 1
Travoprost 0.004% Ophthalmic Solution (Travatan) 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Low Tension Glaucoma trials report? (7)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Asthma 1 1
Cerebrovascular accident 1 1
Dementia 1 1
Herpes zoster 1 1
Intestinal obstruction 1 1

Which publications cover Low Tension Glaucoma? (33)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages