Condition (MeSH)
Corneal Perforation
ClinicalTrials.gov lists 7 trials for Corneal Perforation or a narrower condition beneath it.
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Trials per phase
7 of the 7 trials are tagged with Corneal Perforation itself; the rest are tagged with a narrower condition beneath it.
When did Corneal Perforation trials start? (6)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2/3
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 1 |
| 2022 | 1 |
| 2020 | 1 |
| 2018 | 2 |
| 2014 | 1 |
| 2005 | 1 |
No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 7 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Corneal Perforation trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2/3 | 1 |
| Not applicable | 2 |
| Observational | 3 |
How many Corneal Perforation trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 4 |
| Terminated | 1 |
| Withdrawn | 1 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Corneal Perforation trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. | 1 |
| Farwaniya Hospital | 1 |
Which publications cover Corneal Perforation? (7)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Combined Platelet Rich Plasma and Amniotic membrane in the treatment of Perforated Corneal Ulcers. | European journal of ophthalmology | 2022 | Yes |
| Management of corneal perforations: An update. | Indian journal of ophthalmology | 2020 | Yes |
| Predictors of Corneal Perforation or Need for Therapeutic Keratoplasty in Severe Fungal Keratitis: A Secondary Analysis of the Mycotic Ulcer Treatment Trial II. | JAMA ophthalmology | 2017 | Yes |
| Cyclosporine for Dry Eye Associated With Nivolumab: A Case Progressing to Corneal Perforation. | Cornea | 2016 | Yes |
| Tenons Patch Graft in the Management of Large Corneal Perforations. | Cornea | 2016 | Yes |
Showing 5 of 7 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.