Condition (MeSH)
End Stage Liver Disease
ClinicalTrials.gov lists 151 trials for End Stage Liver Disease or a narrower condition beneath it.
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Trials per phase (log scale)
151 of the 151 trials are tagged with End Stage Liver Disease itself; the rest are tagged with a narrower condition beneath it.
When did End Stage Liver Disease trials start? (28)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 17
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 7 |
| 2025 | 5 |
| 2024 | 10 |
| 2023 | 9 |
| 2022 | 17 |
| 2021 | 7 |
| 2020 | 7 |
| 2019 | 8 |
| 2018 | 12 |
| 2017 | 6 |
Showing 10 of 28 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 9 trials starting in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 18 trials still running at the 2026-10-09 snapshot; registered median of 34 months across 87 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are End Stage Liver Disease trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 8 |
| Phase 1/2 | 11 |
| Phase 2 | 4 |
| Phase 2/3 | 1 |
| Phase 3 | 7 |
| Phase 4 | 8 |
| Not applicable | 58 |
| Observational | 54 |
How many End Stage Liver Disease trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 21 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 8 |
| Completed | 67 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Conventional Treatment | 2 |
| Antibiotics | 2 |
| Umbilical Cord Mesenchymal Stem Cell | 1 |
| No Interventions | 1 |
| Fecal Microbiota Transplantation | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do End Stage Liver Disease trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Death | 40 | 1 |
| Bile duct stenosis | 26 | 1 |
| Liver transplant rejection | 26 | 1 |
| Acute kidney injury | 25 | 1 |
| Anaemia | 9 | 1 |
Showing 5 of 10 adverse events.
Which publications cover End Stage Liver Disease? (242)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Validation of a Pretransplant Risk Prediction Model for Early Allograft Dysfunction After Living-donor Liver Transplantation. | Transplantation | 2025 | Yes |
| Home-based LIver FrailTy Intervention (LIFT) in Transplant Candidates: A Feasibility Study. | Transplantation | 2025 | Yes |
| Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis. | The American journal of gastroenterology | 2024 | Yes |
| Growth Hormone Therapy in Decompensated Cirrhosis: An Open-Label, Randomized Control Trial. | The American journal of gastroenterology | 2024 | Yes |
| Extracorporeal Immunomodulation Therapy in Acute Chronic Liver Failure With Multiorgan Failure: First in Human Use. | ASAIO journal (American Society for Artificial Internal Organs : 1992) | 2024 | Yes |
Showing 5 of 242 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.