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Condition (MeSH)

End Stage Liver Disease

ClinicalTrials.gov lists 151 trials for End Stage Liver Disease or a narrower condition beneath it.

MeSH D058625 Digestive System Diseases C06
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Phase 1 Phase 1 8 Phase 1/2 Phase 1/2 11 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 7 Phase 4 Phase 4 8 Not applicable Not applicable 58 Observational Observational 54 Phase 1 Phase 1 8 Phase 1/2 Phase 1/2 11 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 7 Phase 4 Phase 4 8 Not applicable Not applicable 58 Observational Observational 54

Trials per phase (log scale)

151 of the 151 trials are tagged with End Stage Liver Disease itself; the rest are tagged with a narrower condition beneath it.

Get the End Stage Liver Disease report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did End Stage Liver Disease trials start? (28)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 17

1994: 1 trials (Observational 1) 1999: 1 trials (Not applicable 1) 2000: 2 trials (Not applicable 1, Phase 4 1) 2001: 1 trials (Not applicable 1) 2002: 1 trials (Phase 4 1) 2003: 2 trials (Observational 1, Phase 1/2 1) 2004: 1 trials (Phase 4 1) 2006: 4 trials (Observational 1, Not applicable 1, Phase 1/2 1, Phase 1 1) 2007: 2 trials (Observational 1, Phase 3 1) 2008: 3 trials (Phase 3 3) 2009: 2 trials (Not applicable 1, Phase 1/2 1) 2010: 2 trials (Observational 2) 2011: 11 trials (Observational 7, Not applicable 2, Phase 2 1, Phase 1/2 1) 2012: 7 trials (Observational 3, Phase 1/2 3, Phase 1 1) 2013: 4 trials (Observational 2, Not applicable 1, Phase 1 1) 2014: 7 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 1/2 1) 2015: 5 trials (Observational 4, Phase 1 1) 2016: 7 trials (Observational 2, Not applicable 4, Phase 3 1) 2017: 6 trials (Not applicable 3, Phase 4 1, Phase 3 1, Phase 1/2 1) 2018: 12 trials (Observational 3, Not applicable 9) 2019: 8 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2 1) 2020: 7 trials (Observational 2, Not applicable 5) 2021: 7 trials (Observational 3, Not applicable 1, Phase 4 1, Phase 2 1, Phase 1 1) 2022: 17 trials (Observational 7, Not applicable 6, Phase 4 1, Phase 2/3 1, Phase 2 1, Phase 1 1) 2023: 9 trials (Observational 3, Not applicable 6) 2024: 10 trials (Observational 3, Not applicable 4, Phase 1/2 1, Phase 1 2) 2025: 5 trials (Observational 2, Not applicable 3)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 7
2025 5
2024 10
2023 9
2022 17
2021 7
2020 7
2019 8
2018 12
2017 6

Forecast of the full-year count, planned starts included, not rows of this table: about 9 trials starting in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 18 trials still running at the 2026-10-09 snapshot; registered median of 34 months across 87 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are End Stage Liver Disease trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 8
Phase 1/2 11
Phase 2 4
Phase 2/3 1
Phase 3 7
Phase 4 8
Not applicable 58
Observational 54

How many End Stage Liver Disease trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 21
Enrolling by invitation 2
Active, not recruiting 8
Completed 67

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Conventional Treatment 2
Antibiotics 2
Umbilical Cord Mesenchymal Stem Cell 1
No Interventions 1
Fecal Microbiota Transplantation 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do End Stage Liver Disease trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Death 40 1
Bile duct stenosis 26 1
Liver transplant rejection 26 1
Acute kidney injury 25 1
Anaemia 9 1

Which publications cover End Stage Liver Disease? (242)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

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