Condition (MeSH)
Intraoperative Awareness
ClinicalTrials.gov lists 54 trials for Intraoperative Awareness or a narrower condition beneath it. Başakşehir Çam & Sakura City Hospital has the most among industry and government lead sponsors, with 2.
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Trials per phase (log scale)
54 of the 54 trials are tagged with Intraoperative Awareness itself; the rest are tagged with a narrower condition beneath it.
When did Intraoperative Awareness trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 3 |
| 2024 | 2 |
| 2023 | 2 |
| 2022 | 3 |
| 2021 | 7 |
| 2020 | 3 |
| 2019 | 4 |
| 2018 | 7 |
| 2017 | 4 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 3.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 32 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 32 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Intraoperative Awareness trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 3 |
| Not applicable | 21 |
| Observational | 27 |
How many Intraoperative Awareness trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 4 |
| Active, not recruiting | 3 |
| Completed | 30 |
| Suspended | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Intraoperative Awareness trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Başakşehir Çam & Sakura City Hospital | 2 |
Which drugs are being tested for Intraoperative Awareness? (6)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PROPOFOL | 3 |
| DEXMEDETOMIDINE | 2 |
| Isoproterenol | 1 |
| Nitrous Oxide | 1 |
| Esmolol | 1 |
Showing 5 of 6 drugs.
Interventions as named in the registry (9)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| 1% Sevoflurane | 3 |
| We do not modify the normale general anesthesia delivery. We note the concentration of propofol at the effector site of body movementsand awakening | 1 |
| General Anesthesia | 1 |
| Remimazolam TIVA | 1 |
| Sevoflurane Inhalant Product | 1 |
Showing 5 of 9 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Intraoperative Awareness trials report? (4)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Cardiac arrest | 0 | 1 |
| Death | 0 | 1 |
| Seizure | 0 | 1 |
| Stroke | 0 | 1 |
Which publications cover Intraoperative Awareness? (33)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Frontal electroencephalogram reveals emergence-like brain activity occurring during transition periods in cardiac surgery. | British journal of anaesthesia | 2020 | Yes |
| Protocol for direct reporting of awareness in maternity patients (DREAMY): a prospective, multicentre cohort study of accidental awareness during general anaesthesia. | International journal of obstetric anesthesia | 2020 | Yes |
| Bispectral index for improving intraoperative awareness and early postoperative recovery in adults. | The Cochrane database of systematic reviews | 2019 | Yes |
| MOTANA: study protocol to investigate motor cerebral activity during a propofol sedation. | Trials | 2019 | Yes |
| Dreaming and awareness during dexmedetomidine- and propofol-induced unresponsiveness. | British journal of anaesthesia | 2018 | Yes |
Showing 5 of 33 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.