Condition (MeSH)
Lennox Gastaut Syndrome
ClinicalTrials.gov lists 68 trials for Lennox Gastaut Syndrome or a narrower condition beneath it.
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Trials per phase
68 of the 68 trials are tagged with Lennox Gastaut Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Lennox Gastaut Syndrome trials start? (23)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 4 |
| 2024 | 5 |
| 2023 | 2 |
| 2022 | 6 |
| 2021 | 3 |
| 2020 | 3 |
| 2019 | 4 |
| 2018 | 4 |
| 2017 | 4 |
Showing 10 of 23 earlier years.
No forecast is made for this condition: it averages 4.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 35 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 33 months across 36 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Lennox Gastaut Syndrome trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 6 |
| Phase 1/2 | 3 |
| Phase 2 | 6 |
| Phase 3 | 25 |
| Phase 4 | 6 |
| Not applicable | 8 |
| Observational | 11 |
| Expanded access | 3 |
How many Lennox Gastaut Syndrome trials are recruiting? (10)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 5 |
| Enrolling by invitation | 3 |
| Active, not recruiting | 5 |
| Available | 2 |
Showing 5 of 10 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Lennox Gastaut Syndrome trials? (11)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Jazz Pharmaceuticals | 7 |
| Takeda | 7 |
| Longboard Pharmaceuticals | 5 |
| Eisai Inc. | 4 |
| SK Life Science, Inc. | 4 |
Showing 5 of 11 sponsors.
Which drugs are being tested for Lennox Gastaut Syndrome? (7)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Cannabidiol | 11 |
| Soticlestat | 5 |
| Rufinamide | 5 |
| Carisbamate | 4 |
| LP352 | 4 |
Showing 5 of 7 drugs.
Interventions as named in the registry (8)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Topiramate IR | 3 |
| Epidiolex 100 mg/mL Oral Solution | 2 |
| Clobazam Low Dose | 1 |
| Clobazam Medium Dose | 1 |
| CanniMed® 1:20 | 1 |
Showing 5 of 8 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Lennox Gastaut Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Status epilepticus | 154 | 12 |
| Pneumonia | 139 | 15 |
| Convulsion | 112 | 4 |
| Seizure | 69 | 8 |
| Pyrexia | 40 | 7 |
Showing 5 of 10 adverse events.
Which publications cover Lennox Gastaut Syndrome? (32)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 32 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Lennox-Gastaut syndrome | Point prevalence | 1-5 / 10 000 | Europe | Not stated | Exact |
| Lennox-Gastaut syndrome | Annual incidence | 1-9 / 1 000 000 | Europe | Not stated | Exact |
| Lennox-Gastaut syndrome | Point prevalence | 1-5 / 10 000 | Europe | Not stated | Exact |
| Lennox-Gastaut syndrome | Point prevalence | 1-5 / 10 000 | Europe | Not stated | Unspecified |
| Lennox-Gastaut syndrome | Annual incidence | 1-9 / 1 000 000 | Europe | Not stated | Exact |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Lennox-Gastaut syndrome | 2382 | Exact | Orphadata Science knowledge files, Product 1 |
| Lennox-Gastaut syndrome | 2382 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.