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Research supplier
Xenometrix
Xenometrix is listed as a small business research supplier in the Scientist.com network, with 4 sites in 2 countries and 1 service area.
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Sites
4
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Compliance and Quality Control Measures
- Endocrine Screening Screening to determine risk due to disruption of the endocrine system.
Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
Human Biological Samples
- Ex Vivo Skin Explants Aquire Ex vivo skin explants
In Vitro ADME
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
In Vitro Assays
- Cell Proliferation Measure cell number, cell viability and cell division.
- Epidermal Sensitization Assay (EpiSensA): OECD 442D Validated in vitro skin sensitization
- Heparin Potency Tests Heparin potency tests measure the anticoagulant (blood-thinning) activity of the medication to ensure safety, efficacy, and correct dosing
In Vitro Pharmacology
- Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations
Show all 28 services
REACH Services
- In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
- In Vitro Skin Sensitization Determine whether a drug or cosmetic product may cause dermal sensitization.
- OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
- OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
- OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
- OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
Show all 7 in REACH Services
- OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
Safety Pharmacology
- Endocrine Disruptor Screening Use biochemical, cell based or in vivo assays to identify and quantify endocrine-modulating agents.
Testing Services
- Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
- OECD 428: In Vitro Skin Penetration Request OECD 428 services. This method is designed to provide information on absorption of a test substance, (ideally radiolabelled), applied to the surface of a skin sample separating the two chambers (a donor...
- OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
- OECD 442C: Direct Peptide Reactivity Assay (DPRA) Determine whether a test article satisfies the protein-binding criterion for skin sensitizers.
Service areas:
Toxicology
Where it operates
Sites by country, with the cities in each.
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Switzerland 3 sites
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Germany 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Xenometrix offers Ames mutagenicity assay (Ames MPF and Ames II) and cytotoxicity assay services.
- Website
- www.xenometrix.ch
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