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Urosphere SAS
Urosphere SAS is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Biomarkers
- Microalbumin/Creatinine Ratio (MACR) Screen for kidney disease or monitor the extent of kidney damage from disease complication.
- Myeloperoxidase Testing Detect inflammatory markers and determine the risk for atherosclerosis or arterial plaque rupturing.
Cell Culture and Characterization
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Chemical and Compound Testing
- Product Testing Ensure product quality standards are met.
Developmental and Reproductive Toxicology (DART)
- Fertility and Embryonic Development Study (Segment I) - Mouse Conduct a study to determine the effect of your compound on the estrous cycle, spermatogenesis/male reproductive organs, fertility of parents, and development of the embryo in mice.
- Fertility and Embryonic Development Study (Segment I) - Rat Conduct a study to determine the effect of your compound on the estrous cycle, spermatogenesis/male reproductive organs, fertility of parents, and development of the embryo in rats.
Disease Models
- Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
- Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
- General Pain Models Measure therapeutic endpoints in animal models of general pain.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
Show all 14 in Disease Models
- Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
- Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
- Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
- Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
- Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
Show all 56 services
General in vivo Toxicology
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Human Biological Samples
- Existing PDX models For requesting Existing PDX models
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
In Vitro Assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- In Vitro Fertilization Models Measure oocyte maturation, embryo development in culture and sperm fertilizing ability.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Custom Model Development Develop a custom disease model.
- Fresh Functional Human Tissue Contractile Force Assays Use fresh functional human tissue to assess contractile force with various compounds.
- Fresh Functional Human Tissue Efficacy Assays Use fresh functional human tissue to assess pre-clinical efficacy of test compounds.
- Fresh Functional Human Tissue Ion Channel Activity Assays Use fresh functional human tissue to assess ion channel activity with various compounds.
- Fresh Functional Human Tissue Muscle Contraction Assays Use fresh functional human tissue to assess muscle contraction with various compounds.
Show all 9 in Model Development
- Fresh Functional Human Tissue Muscle Relaxation Assays Use fresh functional human tissue to assess muscle relaxation with various compounds.
- Fresh Functional Human Tissue Safety Assays Use fresh functional human tissue to assess pre-clinical safety of test compounds.
- Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
Oncology Models
- Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
- Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
- Urinary System PDX Patient Derived Xenografts relating to organs that comprise the Urinary system. This includes, but is not limited to, samples from the Kidneys, Liver, and Bladder.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Other services
- New Request
- Pfizer Sourcing Request Initiate a new request supported by a Pfizer Sourcing Group
Service areas:
Pharmacology
Where it operates
Sites by country, with the cities in each.
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France 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Urosphere offers in vitro and in vivo models for genitourinary pathologies and renal disorders.
- Website
- www.urosphere.com
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