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AbovChem LLC

AbovChem LLC is listed as a mid sized business research supplier in the Scientist.com network, with 5 sites in 3 countries.

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Sites 5
Countries 3

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Chemical and Compound Analysis

  • Chiral Separation Purify therapeutically active isomers of drug candidates.
  • Compound Integrity Analyze the identity and purity of small molecule drug candidates.

Chemistry, Manufacturing and Controls (CMC)

  • Advanced intermediates Sourcing advanced intermediates
  • API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
  • Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
  • Crystallization studies Crystallization studies
  • Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
  • Regulatory Starting Materials Sourcing regulatory starting materials (RSM)

Discovery Chemistry

  • Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
  • Compound Purchase Buy compounds, building blocks or compound libraries.
  • Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
  • Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Show all 10 in Discovery Chemistry 4 more
  • HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
  • Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
  • Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
  • USP Testing Analytical Reagents Acquire chemical reagents, solution concentrates and volumetric solutions used to evaluate items in USP testing.
Show all 35 services 21 more

Drug Development

  • Small Molecule Drug Development Consulting Request consulting services related to small molecule development.

General in vivo Toxicology

  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

In Vitro ADME

  • Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
  • Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
  • CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
  • Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
  • Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
  • Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Show all 8 in In Vitro ADME 2 more
  • Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
  • Reference Standards Find reference standards for assays, tests and services.

In Vitro Pharmacology

  • Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.

In Vivo Pharmacokinetics

  • Mass Balance Elucidate excretory pathways and organ distribution of a parent drug and metabolites

Oncology Models

  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.

Protein Sciences

  • Peptide Derivatives Acquire chemicals that are peptide derivatives.
  • Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.

Safety Pharmacology

  • Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.

Other services

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Website
abovchem.com

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • China Shanghai, Xi'an City 2 sites
  • United States Cranbury, San Diego 2 sites
  • Germany Berlin 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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