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WuXi Advanced Therapies

WuXi Advanced Therapies is listed as a large business research supplier in the Scientist.com network, with 3 sites in 1 country.

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Sites 3
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Large business

Antibodies

  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
  • Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.

Bioimaging

  • Bioimaging Visualize biological process non-invasively in real time.
  • Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
  • Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Cell Culture and Characterization

  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
  • Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
  • Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.
Show all 86 services 74 more

Chemical and Compound Analysis

  • Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
  • Chemical Stability Measure the stability of small molecules in solution.
  • Compound Integrity Analyze the identity and purity of small molecule drug candidates.
  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
  • Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
  • Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Show all 14 in Chemical and Compound Analysis 8 more
  • GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
  • Photostability Measure drug degradation rates after exposure to various light sources.
  • Phototoxicity & Photosensitization Test Test the potential for a product to elicit a reaction under UV exposure.
  • Process Residual Impurities Detection Measure trace levels of impurities.
  • Scanning and Transmission Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.

Chemical and Compound Testing

  • Bacterial Water Analysis Analyzing water samples to identify the bacteria present.
  • Limulus Amebocyte Lysate (LAL) Test Detect bacterial endotoxins in raw materials used for the production of cosmetics products.
  • Product Testing Ensure product quality standards are met.
  • USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
  • USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.
  • USP <85> Bacterial Endotoxin Test Test to detect or quantify bacterial endotoxins that may be present in or on a sample.

Chemistry, Manufacturing and Controls (CMC)

  • Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
  • GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
  • Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.

Clinical Consulting

  • Clinical Protocol Design & Development Creation of clinical protocol document which details how a clinical trial is designed,&nbsp;relating to to the methodology, hypothesis, and operation of clinical trial to ensure the safety of the patients is...

Clinical Trials

  • Post-Marketing (Phase 4) Studies Conduct phase 4 studies for confirming unrecognized safety issues, investigating possible hazards or establishing the expected safety profile of a veterinary medicinal product under market conditions.

Discovery Chemistry

  • Leaching and Aged Leaching Assess the leaching potential of products with studies that follow the formation and movement of metabolites or show restricted leaching under simulated use conditions.

DNA & RNA

  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • Targeted Sequencing/Resequencing Detect variations in a genome subset.

Effectiveness

  • Field Dose Confirmation Studies Conduct an in vivo study to confirm the effectiveness of a selected drug dose in actual field conditions.
  • Field Dose Determination Studies Examine the effectiveness of various therapeutic concentrations and durations against natural infections under a variety of field conditions.
  • In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
  • Laboratory Dose Confirmation Studies Conduct in vivo studies to confirm the effectiveness of a selected drug dose in the lab.
  • Laboratory Dose Determination Studies Compare the effectiveness of three non-zero therapeutic concentrations for various durations to a non-medicated control group, and a non-medicated uninfected control group.

General in vivo Toxicology

  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
  • Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.

In Vitro Assays

  • Microbiology Study microbes and their role in human health.
  • Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.
  • Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation

Model Development

  • Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.

Other Specialty Toxicology

  • Biosafety Testing Consulting Expert advice to conduct safe and responsible biological procedures and practices.
  • Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
  • Raw Materials Testing Verify that raw materials are sterile and not contaminated by mycoplasma, virus or other microorganisms.
  • Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.
  • Tumorigenicity Testing Test tumor-forming properties of cell products.
  • United States Pharmacopeia (USP) Testing Use USP standards to ensure quality of pharmaceuticals, supplements and food ingredients.

Pharmacovigilance

  • GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Protein Sciences

  • Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
  • Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
  • Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
  • Protein Products Find native and recombinant proteins and peptides.
Show all 7 in Protein Sciences 1 more
  • Virus Production Produce high titer viruses, viral expression vectors and vaccines.

Regulatory Consulting

  • Toxicology Data Review Identify relevant toxicological endpoints for “No Observed (Adverse) Effect Level” (NO(A)EL) or “Lowest Observed (Adverse) Effect Level” (LO(A)EL).

Scientific Data Services

  • Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
  • Data Curation Organize and integrate data collected from various sources to ease data discovery and retrieval.
  • Data Infrastructure Design and deploy an information management solution suited to users' specific needs.
  • Data Quality Framework Manage data quality issues to maintain good quality data outputs.

Target Animal and Human Food Safety

  • Target Animal Safety (TAS) Studies Evaluate potential harmful effects associated with the use of a new animal drug in a controlled setting.
  • Tolerance Studies Conduct tolerance studies on target animals of veterinary products.
  • Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
  • Elevated Temperature Stability Determine the stability of a product at elevated temperature.
  • Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
  • Microbiological Sterility Testing Test the presence of viable microorganisms.
  • Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
  • Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Show all 8 in Testing Services 2 more
  • USP <61> Microbial Limits Test Determine whether a substance or preparation complies with an established specification for microbiological quality.
  • USP <62> Microbial Limits Test Determine the presence or absence of specific microorganisms.

Other services

  • New Request &nbsp;

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Philadelphia 3 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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