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Research supplier
Biospective
Biospective is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country and 3 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
- In Vivo Positron Emission Tomography (PET) Imaging Image tumor progression or conduct biodistribution investigations in experimental animals injected with a radiolabeled molecular probe.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
- Magnetic Resonance Imaging Use MRI to obtain chemical and physical information about molecules and map the internal structure of an object.
Show all 10 in Bioimaging
- Medical Imaging Visualize and analyze internal structures in animal models or patients.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
- Positron Emission Tomography (PET) Imaging Use PET imaging with radioactive agent to visualize and measure metabolic processes in the body.
- SPECT-CT and PET-CT Imaging Get images that combine the spatial context of metabolic or biochemical activity with an anatomic image.
Biomarkers
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Show all 7 in Biomarkers
- Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Show all 40 services
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Chemical and Compound Analysis
- Computed Tomography Visualize the internal features of solid objects.
- Fluorescence Mediated Tomography Visualize the spatial distribution of fluorescencently labeled probes and substances.
Disease Models
- Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
- Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Show all 13 in Disease Models
- Morris Water Maze Investigate spatial learning and memory in rodents.
- Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
- Olfactory Testing Models Measure therapeutic endpoints in animal models of olfactory function.
- Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
- Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
In Vitro ADME
- Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Non-Human Biospecimen
- Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Oncology Models
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Canada 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Biospecitve have developed sophisticated, integrated multi-modality platforms to maximize the sensitivity for detection of subtle structural, functional, and molecular changes in response to treatment for a comprehensive understanding of therapeutic efficacy. Our diverse range of services provides our pharmaceutical and biotechnology sponsors with an unparalleled ability to assess novel therapeutic agents in a comprehensive fashion. We offers pathology services including a wide range of histology & immunohistochemistry (IHC) stains in multiple species. We have developed a state-of-the art...
Show the full description
Biospecitve have developed sophisticated, integrated multi-modality platforms to maximize the sensitivity for detection of subtle structural, functional, and molecular changes in response to treatment for a comprehensive understanding of therapeutic efficacy. Our diverse range of services provides our pharmaceutical and biotechnology sponsors with an unparalleled ability to assess novel therapeutic agents in a comprehensive fashion.
We offers pathology services including a wide range of histology & immunohistochemistry (IHC) stains in multiple species. We have developed a state-of-the art technology to provide an efficient and accurate IHC marker quantification facilitating the validation of novel disease-modifying therapeutic agents . Conventional quantitative IHC analysis relies on manual or semi-automated segmentation of a few representative, high-power fields. This labor-intensive process is prone to operator variabilitiy and low sampling, thereby introducing unwanted bias. In contrast, Biospective employs its fully-automated, unbiased, and high-throughput technology to accurately quantify IHC markers.
Biospective utilizes a broad range of imaging modalities to assess the therapeutic potential of novel disease-modifying agents in rodent. We have developed state-of-the-art software to accurately co-register in vivo MRI and 3D quantitative neuropathology measures. Biospective adheres to internationally-accepted practices to ensure the highest possible quality, integrity, and reliability of our studies. Our pre-clinical studies are conducted in the spirit of GLP and clinical studies follow ICH GCP principles.
Biospective performs advanced image processing in human for a broad range of imaging modalities, namely, PET, structural MRI, and functional MRI imaging studies. Only Biospective bridges the gap between pre-clinical studies and clinical trials. Our expert team of scientists works closely with our clients to design mechanism-of-action and efficacy studies that increase the chances of success.
- Website
- www.biospective.com
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