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BioAssay Systems

BioAssay Systems is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Compliance and Quality Control Measures

  • Pesticide Product Testing Use laboratory assays to evaluate the efficacy, safety and selectivity of a pesticide under GLP standards.

Antibodies

  • Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Immunodetection Use antibodies to identify a protein or antigen.

Biomarkers

  • Adipogenesis Assay Detect and quantify intracellular triglyceride accumulation in adipocytes.
  • Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Bone Resorption Assay Functionally analyze osteoclast activity in vitro.
  • Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
  • Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Show all 19 in Biomarkers 13 more
  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
  • Histamine Release Assay Use in vivo or in vitro assays to measure the release of histamine in response to an allergen stimulation.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
  • Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
  • Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
  • Myeloperoxidase Testing Detect inflammatory markers and determine the risk for atherosclerosis or arterial plaque rupturing.
  • Osteoclasts Measure osteoclast activity and bone resorption in human, mouse or rat assays.
  • Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
  • Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Cell Culture and Characterization

  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Bacterial Cell Culture Culture and Grow bacterial cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
  • Yeast Cell Culture Grow yeast strains or species.
Show all 131 services 115 more

Chemical and Compound Analysis

  • Chemical Stability Measure the stability of small molecules in solution.
  • Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
  • Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 7 in Chemical and Compound Analysis 1 more
  • Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.

Chemical and Compound Testing

  • Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
  • Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
  • Product Testing Ensure product quality standards are met.

Chemistry, Manufacturing and Controls (CMC)

  • Analytical Development and Validation Request services related to Analytical Development and Validation
  • API and Drug Product Stability Testing API and Drug Product Stability Testing.
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.

Clinical Trials

  • Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Data Science/Bioinformatics

  • Discovery Biomarker Analytics An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.

Discovery Chemistry

  • Natural Product Screening Screen large natural product collections for therapeutic activity.
  • Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...

DNA & RNA

  • Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.

Effectiveness

  • In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
  • Minimum Bactericidal Concentration (MBC) Test Assess the bactericidal activity of a test compound.

Farm & Livestock Solutions

  • Soil Soluble Salts Test Identify the soluble salt components of a soil sample to direct remedial steps.
  • Soil Testing Use various tests to characterize a soil sample.

Food Safety & Regulations

  • Carbohydrate Testing Determine the types and concentrations of carbohydrates in foods for nutritional labeling, quality control, and for identifying possible adulteration.
  • Dietary Enzyme Testing Verify actual enzyme activity in the final dietary product.
  • Phthalates Analysis Determine the absence of phthalates in food and dietary supplements.

In Vitro ADME

  • CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
  • Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
  • Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
  • Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
  • Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
  • Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.

In Vitro Assays

  • Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Assay Development Construct or create new assays or modify existing ones.
  • Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Show all 19 in In Vitro Assays 13 more
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Glucose Release Assay Determine free glucose levels in biological samples.
  • Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
  • High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
  • HTS Assay Development Develop assays to use in high throughput screening.
  • Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
  • Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
  • Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
  • Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.
  • Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
  • Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
  • Serine Protease Assay Detect apoptosis by measuring protease activity.

In Vitro Pharmacology

  • ATP Competitive Study Determine whether or not a compound is competitive with ATP.
  • Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
  • Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Show all 21 in In Vitro Pharmacology 15 more
  • In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
  • Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
  • Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
  • Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
  • Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
  • Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
  • Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
  • Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
  • Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
  • Protease Assay Measure protease activity in biochemical and cell-based assays.
  • Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
  • Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
  • Target Identification Identify the target(s) of a biologically active substance.
  • Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
  • Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

In Vivo Pharmacokinetics

  • Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
  • Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.
  • Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
  • Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.

Nanotechnology

  • Nanoparticle Conjugation and Functionalization Modify biomolecules to enhance structure and function.

New Product Development

  • Quantitative Descriptive Food Analysis Apply a variety of methods to quantify the sensory properties of distinct product attributes.

Other Specialty Toxicology

  • Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety

Protein Sciences

  • Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
  • Cytokines Find recombinant cytokines or cytokine assays.
  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
  • Fluorescence Polarization Investigate receptor-ligand interactions, protein-DNA interactions, proteolysis and membrane fluidity.
  • Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
Show all 11 in Protein Sciences 5 more
  • Low Density Lipoprotein (LDL) Uptake Assay Investigate low density lipoprotein uptake and regulation at the cellular level.
  • Phosphorylation Analysis Identify phosphorylation sites in target proteins.
  • Protein Binding Determine drug-protein binding interactions
  • Protein Chemistry Request information or a price quote for Protein Chemistry services
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

REACH Services

  • OECD 451: Carcinogenicity Studies The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test...

Target Animal and Human Food Safety

  • Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
  • Elevated Temperature Stability Determine the stability of a product at elevated temperature.
  • In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
  • ISO 11930: Preservative Test Evaluate the antimicrobial stabilization of a cosmetic product as per ISO 11930.
  • Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
  • PAO Stability Trial Assess the stability of a consumer product under certain storage conditions.
Show all 7 in Testing Services 1 more
  • Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.

Other services

  • New Request  

Service areas:

Biology Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Hayward 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

BioAssay Systems provides assay kits, assay development and assay services.

Website
www.bioassaysys.com

Source: Scientist.com supplier network, written by the supplier

Supplier diversity

SAM.gov small-business designations

Minority-owned

US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.

Source: U.S. federal System for Award Management (SAM.gov), self-certified by the supplier

Get the BioAssay Systems report as a PDF

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Sources: Scientist.com supplier network, U.S. federal System for Award Management (SAM.gov).

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