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Pion Inc.

Pion Inc. is listed as a small business research supplier in the Scientist.com network, with 3 sites in 2 countries and 1 service area.

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Sites 3
Countries 2

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Chemical and Compound Analysis

  • Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
  • API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
  • Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
  • Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
  • Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
  • Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Show all 7 in Chemical and Compound Analysis 1 more
  • UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Chemistry, Manufacturing and Controls (CMC)

  • API and Drug Product Stability Testing API and Drug Product Stability Testing.
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
  • Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.

Data Science/Bioinformatics

  • In Silico ADME-PK Predictions Use computer software to simulate in vivo physiological conditions of animals or humans to predict ADME-PK properties.

Discovery Chemistry

  • Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
  • UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Show all 25 services 12 more

In Vitro ADME

  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
  • Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
  • Nasal Permeability Test for passive diffusion and active transport in nasal permeability models.
  • Ocular Permeability Measure passive diffusion and active transport of drugs across confluent ocular epithelial cells.
  • Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.

Lab Supplies, Facilities, and Equipment

  • Lab Equipment Installation & Calibration Install new or refurbish used laboratory equipment and calibrate to reference standards.
  • Lab Equipment Maintenance & Repair Conduct repairs for laboratory equipment or routine and preventative maintenance.
  • Rent-to-Purchase Lab Equipment Obtain rent-to-purchase laboratory equipment and the corresponding contracts.

Testing Services

  • Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.

Other services

  • New Request  

Service areas:

DMPK

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Forest Row 2 sites
  • United States Billerica 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

pION offers compound profiling, dissolution, permeability assays, physicochemical profiles, pharmacokinetic profiles, and degradation studies.

Professional associations
AAPS
Website
www.pion-inc.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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