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Abzena
Abzena is listed as a large business research supplier in the Scientist.com network, with 5 sites in 2 countries.
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Sites
5
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
- Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Show all 21 in Antibodies
- Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
- Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
- Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
- Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
- Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
- Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
- Immunodetection Use antibodies to identify a protein or antigen.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
- Integrated Antibody Development Package-US Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
- Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
- Recombinant Antibody Production Request services related to antibody production services.
- Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
- T Cell Epitope Characterization Evaluate the potency and immunodominance of T-cell epitopes within a molecule.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Show all 115 services
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
Show all 16 in Chemical and Compound Analysis
- Impurities in API Risk assessment Create a risk-based control strategy to determine any impurities in Active Pharmaceutical Ingredients (API).
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Structural Chemistry Examine the relationship between protein structure and function.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API and drug product storage and release API and drug product storage and release
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
Show all 16 in Chemistry, Manufacturing and Controls (CMC)
- Bulk Manufacturing Find facilities for large-scale mass production.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Compendial test methods Run Compendial test methods (e.g., KF)
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
- Formulation Services Assistance when determining the look, texture, fragrance of a product with compatibility with product packaging, knowledge of competitive performance traits and product shelf life.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
- Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
- Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Data Science/Bioinformatics
- Discovery Predictive Analytics Analytical approaches to predict how a drug target behaves in a given environment.
- In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.
Discovery Chemistry
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
- In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
- Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Show all 7 in Discovery Chemistry
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
Drug Development
- Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
Human Biological Samples
- Cell Line and Cellular Services Promotion for Cells and Cell lines
In Vitro ADME
- Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
Nanotechnology
- Nanoparticle Conjugation and Functionalization Modify biomolecules to enhance structure and function.
- Nanoparticle Synthesis Create nano-level structures with unique features.
Protein Sciences
- Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Show all 19 in Protein Sciences
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
- Phage Display Use in vitro screening method to identify protein binding partners.
- Protein Binding Determine drug-protein binding interactions
- Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
Safety Pharmacology
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Characteristic Testing Characterization of physical and chemical properties of raw materials
- Raw Material Microbiological Testing Examples of which include Microbial Content using USP <61> and <62> and other standards, LAL Endotoxin, Ames Mutagenicity and Sterility.
Other services
- EpiScreen™ - Ex Vivo Immunogenicity Assessment Assess the potential immunogenicity of proteins and antibodies ex vivo by measuring CD4+ T-cell responses.
- New Request
Where it operates
Sites by country, with the cities in each.
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United States 4 sites
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United Kingdom 1 site
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