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Hypha Discovery Ltd

Hypha Discovery Ltd is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 4 service areas.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Chemical and Compound Analysis

  • Natural Product Libraries Find microbial, botanical and marine sources of natural products.
  • NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.

Chemistry, Manufacturing and Controls (CMC)

  • API and Drug Product Stability Testing API and Drug Product Stability Testing.
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Discovery Chemistry

  • Certified Standards Find certified standards for assays, tests and services.
  • Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
  • Natural Product Screening Screen large natural product collections for therapeutic activity.

Environmental Assessment

  • Environment Fate Studies Evaluate the behavior of veterinary drugs and additives under controlled field and lab conditions.

In Vitro ADME

  • Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
  • Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
  • Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
  • Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
  • Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
  • Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Show all 12 in In Vitro ADME 6 more
  • Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
  • Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
  • No Label Methods Use mass spectrometry to detect and identify non-radiolabeled drug intermediates in pre-clinical samples.
  • Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
  • Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
  • Reference Standards Find reference standards for assays, tests and services.
Show all 24 services 8 more

Personal Care

  • Natural Products Find extracts from native living organisms with potential therapeutic effects.

Other services

  • New Request  

Service areas:

Biology Chemistry DMPK Toxicology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Milton Park, Abingdon 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Hypha Discovery™ Ltd. is a leading natural products hit compound discovery company, specialising in the identification of novel, biologically active small molecules for pharmaceutical development. Hypha also provides fermentation and compound purification services.

Professional associations
ACS
Website
www.hyphadiscovery.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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