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PharmaBlock
PharmaBlock is listed as a large business research supplier in the Scientist.com network, with 9 sites in 3 countries and 2 service areas.
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Sites
9
Countries
3
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
Show all 15 in Chemical and Compound Analysis
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Impurities in API Risk assessment Create a risk-based control strategy to determine any impurities in Active Pharmaceutical Ingredients (API).
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
- Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Chemistry, Manufacturing and Controls (CMC)
- Advanced intermediates Sourcing advanced intermediates
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API and Drug Product Storage and Distribution API and Drug Product Storage and Distribution.
- API and drug product storage and release API and drug product storage and release
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
Show all 33 in Chemistry, Manufacturing and Controls (CMC)
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
- Bulk Manufacturing Find facilities for large-scale mass production.
- Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
- Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Clinical supply management Clinical supply management
- Compendial test methods Run Compendial test methods (e.g., KF)
- Crystallization studies Crystallization studies
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
- Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- Formulation Services Assistance when determining the look, texture, fragrance of a product with compatibility with product packaging, knowledge of competitive performance traits and product shelf life.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
- ICH-compliant stability testing Perform ICH-compliant stability testing
- Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.
- Milling, grinding, spray-drying Milling, grinding, spray-drying
- Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
- Raw Materials & Ingredients Purchase raw materials, ingredients, or chemicals for personal care, cosmetic, consumer health, and beauty products and substances.
- Regulatory Starting Materials Sourcing regulatory starting materials (RSM)
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Tablet Manufacturing Use automatic or semi-automatic machinery to create various standard and non-standard tablets.
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
- Thermo Scientific iCAP Q ICP-MS Expand your analytical capabilities with this complete trace elemental analysis solution for your high-throughput lab.
Show all 80 services
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Compound Purchase Buy compounds, building blocks or compound libraries.
- Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Show all 27 in Discovery Chemistry
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
- Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- Intermediate Synthesis Synthesize reactive intermediates, do API route scouting, optimize process development and do compound scale-up.
- Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Drug Development
- Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
Protein Sciences
- Peptide Derivatives Acquire chemicals that are peptide derivatives.
Testing Services
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Other services
- New Request
Service areas:
Chemistry
Manufacturing
Where it operates
Sites by country, with the cities in each.
-
China 5 sites
-
United States 3 sites
-
Switzerland 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
PharmaBlock provides synthetic chemistry, medicinal chemistry, custom synthesis, and library design.
- Professional associations
- ACS, DCAT
- Website
- www.pharmablock.com
Work with PharmaBlock on Scientist.com
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